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Mariano J. Alvarez
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Journal Articles

A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies

Prabhjot S. Mundi, Filemon S. Dela Cruz, Adina Grunn, Daniel Diolaiti, Audrey Mauguen, Allison R. Rainey, Kristina Guillan, Armaan Siddiquee, Daoqi You, Ronald Realubit, Charles Karan, Michael V. Ortiz, Eugene F. Douglass, Jr, Melissa Accordino, Suzanne Mistretta, Frances Brogan, Jeffrey N. Bruce, Cristina I. Caescu, Richard D. Carvajal, Katherine D. Crew, Guarionex Decastro, Mark Heaney, Brian S. Henick, Dawn L. Hershman, June Y. Hou, Fabio M. Iwamoto, Joseph G. Jurcic, Ravi P. Kiran, Michael D. Kluger, Teri Kreisl, Nicole Lamanna, Andrew B. Lassman, Emerson A. Lim, Gulam A. Manji, Guy M. McKhann, James M. McKiernan, Alfred I. Neugut, Kenneth P. Olive, Todd Rosenblat, Gary K. Schwartz, Catherine A. Shu, Michael B. Sisti, Ana Tergas, Reena M. Vattakalam, Mary Welch, Sven Wenske, Jason D. Wright, Peter Canoll, Hanina Hibshoosh, Kevin Kalinsky, Mahalaxmi Aburi, Peter A. Sims, Mariano J. Alvarez, Andrew L. Kung, Andrea Califano
Journal: Cancer Discovery
Cancer Discov (2023) 13 (6): 1386–1407.
https://doi.org/10.1158/2159-8290.CD-22-1020
Published: 02 June 2023
View articletitled, A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies
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Includes: Supplementary data
Journal Articles

OncoLoop: A Network-Based Precision Cancer Medicine Framework

Alessandro Vasciaveo, Juan Martín Arriaga, Francisca Nunes de Almeida, Min Zou, Eugene F. Douglass, Jr, Florencia Picech, Maho Shibata, Antonio Rodriguez-Calero, Simone de Brot, Antonina Mitrofanova, Chee Wai Chua, Charles Karan, Ronald Realubit, Sergey Pampou, Jaime Y. Kim, Stephanie N. Afari, Timur Mukhammadov, Luca Zanella, Eva Corey, Mariano J. Alvarez, Mark A. Rubin, Michael M. Shen, Andrea Califano, Cory Abate-Shen
Journal: Cancer Discovery
Cancer Discov (2023) 13 (2): 386–409.
https://doi.org/10.1158/2159-8290.CD-22-0342
Published: 06 February 2023
View articletitled, OncoLoop: A Network-Based Precision Cancer Medicine Framework
Open the PDF for OncoLoop: A Network-Based Precision Cancer Medicine Framework in another window
Includes: Supplementary data
Journal Articles

Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

Presha Rajbhandari, Gonzalo Lopez, Claudia Capdevila, Beatrice Salvatori, Jiyang Yu, Ruth Rodriguez-Barrueco, Daniel Martinez, Mark Yarmarkovich, Nina Weichert-Leahey, Brian J. Abraham, Mariano J. Alvarez, Archana Iyer, Jo Lynne Harenza, Derek Oldridge, Katleen De Preter, Jan Koster, Shahab Asgharzadeh, Robert C. Seeger, Jun S. Wei, Javed Khan, Jo Vandesompele, Pieter Mestdagh, Rogier Versteeg, A. Thomas Look, Richard A. Young, Antonio Iavarone, Anna Lasorella, Jose M. Silva, John M. Maris, Andrea Califano
Journal: Cancer Discovery
Cancer Discov (2018) 8 (5): 582–599.
https://doi.org/10.1158/2159-8290.CD-16-0861
Published: 30 April 2018
View articletitled, Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma
Open the PDF for Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma in another window
Includes: Supplementary data