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Lynda Chin
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Journal Articles

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

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Banu Eskiocak, Elizabeth A. McMillan, Saurabh Mendiratta, Rahul K. Kollipara, Hailei Zhang, Caroline G. Humphries, Changguang Wang, Jose Garcia-Rodriguez, Ming Ding, Aubhishek Zaman, Tracy I. Rosales, Ugur Eskiocak, Michael P. Smith, Jessica Sudderth, Kakajan Komurov, Ralph J. Deberardinis, Claudia Wellbrock, Michael A. Davies, Jennifer A. Wargo, Yonghao Yu, Jef K. De Brabander, Noelle S. Williams, Lynda Chin, Helen Rizos, Georgina V. Long, Ralf Kittler, Michael A. White
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 832–851.
https://doi.org/10.1158/2159-8290.CD-16-0955
Published: 01 August 2017
View articletitled, Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma
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Includes: Supplementary data
Journal Articles

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

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Pei-Ling Chen, Whijae Roh, Alexandre Reuben, Zachary A. Cooper, Christine N. Spencer, Peter A. Prieto, John P. Miller, Roland L. Bassett, Vancheswaran Gopalakrishnan, Khalida Wani, Mariana Petaccia De Macedo, Jacob L. Austin-Breneman, Hong Jiang, Qing Chang, Sangeetha M. Reddy, Wei-Shen Chen, Michael T. Tetzlaff, Russell J. Broaddus, Michael A. Davies, Jeffrey E. Gershenwald, Lauren Haydu, Alexander J. Lazar, Sapna P. Patel, Patrick Hwu, Wen-Jen Hwu, Adi Diab, Isabella C. Glitza, Scott E. Woodman, Luis M. Vence, Ignacio I. Wistuba, Rodabe N. Amaria, Lawrence N. Kwong, Victor Prieto, R. Eric Davis, Wencai Ma, Willem W. Overwijk, Arlene H. Sharpe, Jianhua Hu, P. Andrew Futreal, Jorge Blando, Padmanee Sharma, James P. Allison, Lynda Chin, Jennifer A. Wargo
Journal: Cancer Discovery
Cancer Discov (2016) 6 (8): 827–837.
https://doi.org/10.1158/2159-8290.CD-15-1545
Published: 01 August 2016
View articletitled, Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade
Open the PDF for Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

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Guocan Wang, Xin Lu, Prasenjit Dey, Pingna Deng, Chia Chin Wu, Shan Jiang, Zhuangna Fang, Kun Zhao, Ramakrishna Konaparthi, Sujun Hua, Jianhua Zhang, Elsa M. Li-Ning-Tapia, Avnish Kapoor, Chang-Jiun Wu, Neelay Bhaskar Patel, Zhenglin Guo, Vandhana Ramamoorthy, Trang N. Tieu, Tim Heffernan, Di Zhao, Xiaoying Shang, Sunada Khadka, Pingping Hou, Baoli Hu, Eun-Jung Jin, Wantong Yao, Xiaolu Pan, Zhihu Ding, Yanxia Shi, Liren Li, Qing Chang, Patricia Troncoso, Christopher J. Logothetis, Mark J. McArthur, Lynda Chin, Y. Alan Wang, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2016) 6 (1): 80–95.
https://doi.org/10.1158/2159-8290.CD-15-0224
Published: 07 January 2016
View articletitled, Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression
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Includes: Supplementary data
Journal Articles

Dual Roles of RNF2 in Melanoma Progression

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Kunal Rai, Kadir C. Akdemir, Lawrence N. Kwong, Petko Fiziev, Chang-Jiun Wu, Emily Z. Keung, Sneha Sharma, Neha S. Samant, Maura Williams, Jacob B. Axelrad, Amiksha Shah, Dong Yang, Elizabeth A. Grimm, Michelle C. Barton, Denai R. Milton, Timothy P. Heffernan, James W. Horner, Suhendan Ekmekcioglu, Alexander J. Lazar, Jason Ernst, Lynda Chin
Journal: Cancer Discovery
Cancer Discov (2015) 5 (12): 1314–1327.
https://doi.org/10.1158/2159-8290.CD-15-0493
Published: 03 December 2015
View articletitled, Dual Roles of RNF2 in Melanoma Progression
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Includes: Supplementary data
Journal Articles

A Systems Biology Approach to Personalizing Therapeutic Combinations

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Lawrence N. Kwong, Timothy P. Heffernan, Lynda Chin
Journal: Cancer Discovery
Cancer Discov (2013) 3 (12): 1339–1344.
https://doi.org/10.1158/2159-8290.CD-13-0394
Published: 10 December 2013
View articletitled, A Systems Biology Approach to Personalizing Therapeutic Combinations
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Journal Articles

microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma

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Giannicola Genovese, Ayla Ergun, Sachet A. Shukla, Benito Campos, Jason Hanna, Papia Ghosh, Steven N. Quayle, Kunal Rai, Simona Colla, Haoqiang Ying, Chang-Jiun Wu, Sharmistha Sarkar, Yonghong Xiao, Jianhua Zhang, Hailei Zhang, Lawrence Kwong, Katherine Dunn, Wolf Ruprecht Wiedemeyer, Cameron Brennan, Hongwu Zheng, David L. Rimm, James J. Collins, Lynda Chin
Journal: Cancer Discovery
Cancer Discov (2012) 2 (8): 736–749.
https://doi.org/10.1158/2159-8290.CD-12-0111
Published: 09 August 2012
View articletitled, microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma
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Includes: Supplementary data
Journal Articles

PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network

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Haoqiang Ying, Kutlu G. Elpek, Anant Vinjamoori, Stephanie M. Zimmerman, Gerald C. Chu, Haiyan Yan, Eliot Fletcher-Sananikone, Hailei Zhang, Yingchun Liu, Wei Wang, Xiaojia Ren, Hongwu Zheng, Alec C. Kimmelman, Ji-hye Paik, Carol Lim, Samuel R. Perry, Shan Jiang, Brian Malinn, Alexei Protopopov, Simona Colla, Yonghong Xiao, Aram F. Hezel, Nabeel Bardeesy, Shannon J. Turley, Y. Alan Wang, Lynda Chin, Sarah P. Thayer, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2011) 1 (2): 158–169.
https://doi.org/10.1158/2159-8290.CD-11-0031
Published: 17 July 2011
View articletitled, PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
Open the PDF for PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network in another window
Includes: Supplementary data