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Lillian M. Smyth
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Journal Articles

Characteristics and Outcome of AKT1E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry

Free
Lillian M. Smyth, Qin Zhou, Bastien Nguyen, Celeste Yu, Eva M. Lepisto, Monica Arnedos, Michael J. Hasset, Michele L. Lenoue-Newton, Natalie Blauvelt, Semih Dogan, Christine M. Micheel, Chetna Wathoo, Hugo Horlings, Jan Hudecek, Benjamin E. Gross, Ritika Kundra, Shawn M. Sweeney, JianJiong Gao, Nikolaus Schultz, Andrew Zarski, Stuart M. Gardos, Jocelyn Lee, Seth Sheffler-Collins, Ben H. Park, Charles L. Sawyers, Fabrice André, Mia Levy, Funda Meric-Bernstam, Philippe L. Bedard, Alexia Iasonos, Deborah Schrag, David M. Hyman
Journal: Cancer Discovery
Cancer Discov (2020) 10 (4): 526–535.
https://doi.org/10.1158/2159-8290.CD-19-1209
Published: 01 April 2020
View articletitled, Characteristics and Outcome of AKT1E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry
Open the PDF for Characteristics and Outcome of AKT1E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry in another window
Includes: Supplementary data
Journal Articles

Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer

Free
Lillian M. Smyth, Sarina A. Piha-Paul, Helen H. Won, Alison M. Schram, Cristina Saura, Sherene Loi, Janice Lu, Geoffrey I. Shapiro, Dejan Juric, Ingrid A. Mayer, Carlos L. Arteaga, Macarena I. de la Fuente, Adam M. Brufksy, Iben Spanggaard, Morten Mau-Sørensen, Monica Arnedos, Victor Moreno, Valentina Boni, Joohyuk Sohn, Lee S. Schwartzberg, Xavier Gonzàlez-Farré, Andrés Cervantes, François-Clement Bidard, Alexander N. Gorelick, Richard B. Lanman, Rebecca J. Nagy, Gary A. Ulaner, Sarat Chandarlapaty, Komal Jhaveri, Elena I. Gavrila, Catherine Zimel, S. Duygu Selcuklu, Myra Melcer, Aliaksandra Samoila, Yanyan Cai, Maurizio Scaltriti, Grace Mann, Feng Xu, Lisa D. Eli, Melanie Dujka, Alshad S. Lalani, Richard Bryce, José Baselga, Barry S. Taylor, David B. Solit, Funda Meric-Bernstam, David M. Hyman
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (2): 198–213.
https://doi.org/10.1158/2159-8290.CD-19-0966
Published: 05 February 2020
View articletitled, Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer
Open the PDF for Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion–Driven Cancer

Free
Emily K. Slotkin, Daniel Diolaiti, Neerav N. Shukla, Filemon S. Dela Cruz, Jennifer J. Clark, Gunes Gundem, Venkata D. Yellapantula, Max F. Levine, Daoqi You, Peilin Ma, Sagarika Pachhal, Glorymar Ibanez Sanchez, Ryma Benayed, Achim A. Jungbluth, Lillian M. Smyth, Audrey Mauguen, Irena Gushterova, Hongxu Ding, Lee Spraggon, Robert Darnell, Andrea Califano, Marc Ladanyi, Elli Papaemmanuil, Andrew L. Kung, David M. Hyman, Stephen S. Roberts
Journal: Cancer Discovery
Cancer Discov (2019) 9 (5): 605–616.
https://doi.org/10.1158/2159-8290.CD-18-0953
Published: 01 May 2019
View articletitled, Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion–Driven Cancer
Open the PDF for Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion–Driven Cancer in another window
Includes: Supplementary data