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Journal Articles

Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C

Anna E. Maciag, James P. Stice, Bin Wang, Alok K. Sharma, Albert H. Chan, Ken Lin, Devansh Singh, Marcin Dyba, Yue Yang, Saman Setoodeh, Brian P. Smith, Jin Hyun Ju, Stevan Jeknic, Dana Rabara, Zuhui Zhang, Erik K. Larsen, Dominic Esposito, John-Paul Denson, Michela Ranieri, Mary Meynardie, Sadaf Mehdizadeh, Patrick A. Alexander, Maria Abreu Blanco, David M. Turner, Rui Xu, Felice C. Lightstone, Kwok-Kin Wong, Andrew G. Stephen, Keshi Wang, Dhirendra K. Simanshu, Kerstin W. Sinkevicius, Dwight V. Nissley, Eli Wallace, Frank McCormick, Pedro J. Beltran
Journal: Cancer Discovery
Cancer Discov OF1–OF17.
https://doi.org/10.1158/2159-8290.CD-24-0840
Published: 16 January 2025
View article titled, Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRAS<sup>G12C</sup>
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Includes: Supplementary data
Journal Articles

Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

Peter J. Mazzone, Peter B. Bach, Jacob Carey, Caitlin A. Schonewolf, Katalin Bognar, Manmeet S. Ahluwalia, Marcia Cruz-Correa, David Gierada, Sonali Kotagiri, Kathryn Lloyd, Fabien Maldonado, Jesse D. Ortendahl, Lecia V. Sequist, Gerard A. Silvestri, Nichole Tanner, Jeffrey C. Thompson, Anil Vachani, Kwok-Kin Wong, Ali H. Zaidi, Joseph Catallini, Ariel Gershman, Keith Lumbard, Laurel K. Millberg, Jeff Nawrocki, Carter Portwood, Aakanksha Rangnekar, Carolina Campos Sheridan, Niti Trivedi, Tony Wu, Yuhua Zong, Lindsey Cotton, Allison Ryan, Christopher Cisar, Alessandro Leal, Nicholas Dracopoli, Robert B. Scharpf, Victor E. Velculescu, Luke R. G. Pike
Journal: Cancer Discovery
Cancer Discov (2024) 14 (11): 2224–2242.
https://doi.org/10.1158/2159-8290.CD-24-0519
Published: 01 November 2024
View article titled, Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection
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Includes: Supplementary data
Journal Articles

Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs

Shreoshi Pal Choudhuri, Luc Girard, Jun Yi Stanley Lim, Jillian F. Wise, Braeden Freitas, Di Yang, Edmond Wong, Seth Hamilton, Victor D. Chien, Yoon Jung Kim, Collin Gilbreath, Jun Zhong, Sarah Phat, David T. Myers, Camilla L. Christensen, Hanieh Mazloom-Farsibaf, Marcello Stanzione, Kwok-Kin Wong, Yin P. Hung, Anna F. Farago, Catherine B. Meador, Nicholas J. Dyson, Michael S. Lawrence, Sihan Wu, Benjamin J. Drapkin
Journal: Cancer Discovery
Cancer Discov (2024) 14 (5): 804–827.
https://doi.org/10.1158/2159-8290.CD-23-0656
Published: 01 May 2024
View article titled, Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of <em>MYC</em> Paralogs
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Includes: Supplementary data
Journal Articles

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

Chewei Anderson Chang, Jayu Jen, Shaowen Jiang, Azin Sayad, Arvind Singh Mer, Kevin R. Brown, Allison M.L. Nixon, Avantika Dhabaria, Kwan Ho Tang, David Venet, Christos Sotiriou, Jiehui Deng, Kwok-kin Wong, Sylvia Adams, Peter Meyn, Adriana Heguy, Jane A. Skok, Aristotelis Tsirigos, Beatrix Ueberheide, Jason Moffat, Abhyudai Singh, Benjamin Haibe-Kains, Alireza Khodadadi-Jamayran, Benjamin G. Neel
Journal: Cancer Discovery
Cancer Discov (2022) 12 (4): 1022–1045.
https://doi.org/10.1158/2159-8290.CD-20-1265
Published: 01 April 2022
View article titled, Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2<sup>+</sup> Breast Cancer
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Includes: Supplementary data
Journal Articles

Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC

Kwan Ho Tang, Shuai Li, Alireza Khodadadi-Jamayran, Jayu Jen, Han Han, Kayla Guidry, Ting Chen, Yuan Hao, Carmine Fedele, John A. Zebala, Dean Y. Maeda, James G. Christensen, Peter Olson, Argus Athanas, Cynthia A. Loomis, Aristotelis Tsirigos, Kwok-Kin Wong, Benjamin G. Neel
Journal: Cancer Discovery
Cancer Discov (2022) 12 (1): 47–61.
https://doi.org/10.1158/2159-8290.CD-21-0369
Published: 01 January 2022
View article titled, Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC
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Includes: Supplementary data
Journal Articles

Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non–Small Cell Lung Cancer

Francois Gonzalvez, Sylvie Vincent, Theresa E. Baker, Alexandra E. Gould, Shuai Li, Scott D. Wardwell, Sara Nadworny, Yaoyu Ning, Sen Zhang, Wei-Sheng Huang, Yongbo Hu, Feng Li, Matthew T. Greenfield, Stephan G. Zech, Biplab Das, Narayana I. Narasimhan, Tim Clackson, David Dalgarno, William C. Shakespeare, Michael Fitzgerald, Johara Chouitar, Robert J. Griffin, Shengwu Liu, Kwok-kin Wong, Xiaotian Zhu, Victor M. Rivera
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (7): 1672–1687.
https://doi.org/10.1158/2159-8290.CD-20-1683
Published: 01 July 2021
View article titled, Mobocertinib (TAK-788): A Targeted Inhibitor of <em>EGFR</em> Exon 20 Insertion Mutants in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

An Empirical Antigen Selection Method Identifies Neoantigens That Either Elicit Broad Antitumor T-cell Responses or Drive Tumor Growth

Hubert Lam, Lisa K. McNeil, Hanna Starobinets, Victoria L. DeVault, Roger B. Cohen, Przemyslaw Twardowski, Melissa L. Johnson, Maura L. Gillison, Mark N. Stein, Ulka N. Vaishampayan, Arthur P. DeCillis, James J. Foti, Vijetha Vemulapalli, Emily Tjon, Kyle Ferber, Daniel B. DeOliveira, Wendy Broom, Parul Agnihotri, Elizabeth M. Jaffee, Kwok-Kin Wong, Charles G. Drake, Pamela M. Carroll, Thomas A. Davis, Jessica Baker Flechtner
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (3): 696–713.
https://doi.org/10.1158/2159-8290.CD-20-0377
Published: 01 March 2021
View article titled, An Empirical Antigen Selection Method Identifies Neoantigens That Either Elicit Broad Antitumor T-cell Responses or Drive Tumor Growth
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Includes: Supplementary data
Journal Articles

Lower Airway Dysbiosis Affects Lung Cancer Progression

Jun-Chieh J. Tsay, Benjamin G. Wu, Imran Sulaiman, Katherine Gershner, Rosemary Schluger, Yonghua Li, Ting-An Yie, Peter Meyn, Evan Olsen, Luisannay Perez, Brendan Franca, Joseph Carpenito, Tadasu Iizumi, Mariam El-Ashmawy, Michelle Badri, James T. Morton, Nan Shen, Linchen He, Gaetane Michaud, Samaan Rafeq, Jamie L. Bessich, Robert L. Smith, Harald Sauthoff, Kevin Felner, Ray Pillai, Anastasia-Maria Zavitsanou, Sergei B. Koralov, Valeria Mezzano, Cynthia A. Loomis, Andre L. Moreira, William Moore, Aristotelis Tsirigos, Adriana Heguy, William N. Rom, Daniel H. Sterman, Harvey I. Pass, Jose C. Clemente, Huilin Li, Richard Bonneau, Kwok-Kin Wong, Thales Papagiannakopoulos, Leopoldo N. Segal
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (2): 293–307.
https://doi.org/10.1158/2159-8290.CD-20-0263
Published: 02 February 2021
View article titled, Lower Airway Dysbiosis Affects Lung Cancer Progression
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Includes: Supplementary data
Journal Articles

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

Haisheng Zhang, Antje Schaefer, Yichen Wang, Richard G. Hodge, Devon R. Blake, J. Nathaniel Diehl, Alex G. Papageorge, Matthew D. Stachler, Jennifer Liao, Jin Zhou, Zhong Wu, Fahire G. Akarca, Leonie K. de Klerk, Sarah Derks, Mariaelena Pierobon, Katherine A. Hoadley, Timothy C. Wang, George Church, Kwok-Kin Wong, Emanuel F. Petricoin, Adrienne D. Cox, Douglas R. Lowy, Channing J. Der, Adam J. Bass
Journal: Cancer Discovery
Cancer Discov (2020) 10 (2): 288–305.
https://doi.org/10.1158/2159-8290.CD-19-0811
Published: 05 February 2020
View article titled, Gain-of-Function <em>RHOA</em> Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer
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Includes: Multimedia, Supplementary data
Journal Articles

In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma

Fei Li, Qingyuan Huang, Troy A. Luster, Hai Hu, Hua Zhang, Wai-Lung Ng, Alireza Khodadadi-Jamayran, Wei Wang, Ting Chen, Jiehui Deng, Michela Ranieri, Zhaoyuan Fang, Val Pyon, Catríona M. Dowling, Ece Bagdatlioglu, Christina Almonte, Kristen Labbe, Heather Silver, Alexandra R. Rabin, Kandarp Jani, Aristotelis Tsirigos, Thales Papagiannakopoulos, Peter S. Hammerman, Vamsidhar Velcheti, Gordon J. Freeman, Jun Qi, George Miller, Kwok-Kin Wong
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (2): 270–287.
https://doi.org/10.1158/2159-8290.CD-19-0780
Published: 05 February 2020
View article titled, <em>In Vivo</em> Epigenetic CRISPR Screen Identifies <em>Asf1a</em> as an Immunotherapeutic Target in <em>Kras</em>-Mutant Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Innate αβ T Cells Mediate Antitumor Immunity by Orchestrating Immunogenic Macrophage Programming

Mautin Hundeyin, Emma Kurz, Ankita Mishra, Juan Andres Kochen Rossi, Shannon M. Liudahl, Kenna R. Leis, Harshita Mehrotra, Mirhee Kim, Luisana E. Torres, Adesola Ogunsakin, Jason Link, Rosalie C. Sears, Shamilene Sivagnanam, Jeremy Goecks, K.M. Sadeq Islam, Igor Dolgalev, Shivraj Savadkar, Wei Wang, Berk Aykut, Joshua Leinwand, Brian Diskin, Salma Adam, Muhammad Israr, Maeliss Gelas, Justin Lish, Kathryn Chin, Mohammad Saad Farooq, Benjamin Wadowski, Jingjing Wu, Suhagi Shah, Dennis O. Adeegbe, Smruti Pushalkar, Varshini Vasudevaraja, Deepak Saxena, Kwok-Kin Wong, Lisa M. Coussens, George Miller
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (9): 1288–1305.
https://doi.org/10.1158/2159-8290.CD-19-0161
Published: 03 September 2019
View article titled, Innate αβ T Cells Mediate Antitumor Immunity by Orchestrating Immunogenic Macrophage Programming
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Includes: Supplementary data
Journal Articles

Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor

Ciric To, Jaebong Jang, Ting Chen, Eunyoung Park, Mierzhati Mushajiang, Dries J.H. De Clercq, Man Xu, Stephen Wang, Michael D. Cameron, David E. Heppner, Bo Hee Shin, Thomas W. Gero, Annan Yang, Suzanne E. Dahlberg, Kwok-Kin Wong, Michael J. Eck, Nathanael S. Gray, Pasi A. Jänne
Journal: Cancer Discovery
Cancer Discov (2019) 9 (7): 926–943.
https://doi.org/10.1158/2159-8290.CD-18-0903
Published: 01 July 2019
View article titled, Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor
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Includes: Supplementary data
Journal Articles

EZH2 Inhibitors: Take It EZy, It Is All About Context

Vamsidhar Velcheti, Kwok-Kin Wong, Yogen Saunthararajah
Journal: Cancer Discovery
Cancer Discov (2019) 9 (4): 472–475.
https://doi.org/10.1158/2159-8290.CD-19-0090
Published: 01 April 2019
View article titled, EZH2 Inhibitors: Take It EZy, It Is All About Context
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Journal Articles

STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma

Ferdinandos Skoulidis, Michael E. Goldberg, Danielle M. Greenawalt, Matthew D. Hellmann, Mark M. Awad, Justin F. Gainor, Alexa B. Schrock, Ryan J. Hartmaier, Sally E. Trabucco, Laurie Gay, Siraj M. Ali, Julia A. Elvin, Gaurav Singal, Jeffrey S. Ross, David Fabrizio, Peter M. Szabo, Han Chang, Ariella Sasson, Sujaya Srinivasan, Stefan Kirov, Joseph Szustakowski, Patrik Vitazka, Robin Edwards, Jose A. Bufill, Neelesh Sharma, Sai-Hong I. Ou, Nir Peled, David R. Spigel, Hira Rizvi, Elizabeth Jimenez Aguilar, Brett W. Carter, Jeremy Erasmus, Darragh F. Halpenny, Andrew J. Plodkowski, Niamh M. Long, Mizuki Nishino, Warren L. Denning, Ana Galan-Cobo, Haifa Hamdi, Taghreed Hirz, Pan Tong, Jing Wang, Jaime Rodriguez-Canales, Pamela A. Villalobos, Edwin R. Parra, Neda Kalhor, Lynette M. Sholl, Jennifer L. Sauter, Achim A. Jungbluth, Mari Mino-Kenudson, Roxana Azimi, Yasir Y. Elamin, Jianjun Zhang, Giulia C. Leonardi, Fei Jiang, Kwok-Kin Wong, J. Jack Lee, Vassiliki A. Papadimitrakopoulou, Ignacio I. Wistuba, Vincent A. Miller, Garrett M. Frampton, Jedd D. Wolchok, Alice T. Shaw, Pasi A. Jänne, Philip J. Stephens, Charles M. Rudin, William J. Geese, Lee A. Albacker, John V. Heymach
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (7): 822–835.
https://doi.org/10.1158/2159-8290.CD-18-0099
Published: 01 July 2018
View article titled, <em>STK11/LKB1</em> Mutations and PD-1 Inhibitor Resistance in <em>KRAS</em>-Mutant Lung Adenocarcinoma
Open the PDF for <em>STK11/LKB1</em> Mutations and PD-1 Inhibitor Resistance in <em>KRAS</em>-Mutant Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts

Benjamin J. Drapkin, Julie George, Camilla L. Christensen, Mari Mino-Kenudson, Ruben Dries, Tilak Sundaresan, Sarah Phat, David T. Myers, Jun Zhong, Peter Igo, Mehlika H. Hazar-Rethinam, Joseph A. Licausi, Maria Gomez-Caraballo, Marina Kem, Kandarp N. Jani, Roxana Azimi, Nima Abedpour, Roopika Menon, Sotirios Lakis, Rebecca S. Heist, Reinhard Büttner, Stefan Haas, Lecia V. Sequist, Alice T. Shaw, Kwok-Kin Wong, Aaron N. Hata, Mehmet Toner, Shyamala Maheswaran, Daniel A. Haber, Martin Peifer, Nicholas Dyson, Roman K. Thomas, Anna F. Farago
Journal: Cancer Discovery
Cancer Discov (2018) 8 (5): 600–615.
https://doi.org/10.1158/2159-8290.CD-17-0935
Published: 30 April 2018
View article titled, Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts
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Includes: Supplementary data
Journal Articles

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms

Annan Yang, Grit Herter-Sprie, Haikuo Zhang, Elaine Y. Lin, Douglas Biancur, Xiaoxu Wang, Jiehui Deng, Josephine Hai, Shenghong Yang, Kwok-Kin Wong, Alec C. Kimmelman
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (3): 276–287.
https://doi.org/10.1158/2159-8290.CD-17-0952
Published: 01 March 2018
View article titled, Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms
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Includes: Supplementary data
Journal Articles

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Russell W. Jenkins, Amir R. Aref, Patrick H. Lizotte, Elena Ivanova, Susanna Stinson, Chensheng W. Zhou, Michaela Bowden, Jiehui Deng, Hongye Liu, Diana Miao, Meng Xiao He, William Walker, Gao Zhang, Tian Tian, Chaoran Cheng, Zhi Wei, Sangeetha Palakurthi, Mark Bittinger, Hans Vitzthum, Jong Wook Kim, Ashley Merlino, Max Quinn, Chandrasekar Venkataramani, Joshua A. Kaplan, Andrew Portell, Prafulla C. Gokhale, Bart Phillips, Alicia Smart, Asaf Rotem, Robert E. Jones, Lauren Keogh, Maria Anguiano, Lance Stapleton, Zhiheng Jia, Michal Barzily-Rokni, Israel Cañadas, Tran C. Thai, Marc R. Hammond, Raven Vlahos, Eric S. Wang, Hua Zhang, Shuai Li, Glenn J. Hanna, Wei Huang, Mai P. Hoang, Adriano Piris, Jean-Pierre Eliane, Anat O. Stemmer-Rachamimov, Lisa Cameron, Mei-Ju Su, Parin Shah, Benjamin Izar, Manisha Thakuria, Nicole R. LeBoeuf, Guilherme Rabinowits, Viswanath Gunda, Sareh Parangi, James M. Cleary, Brian C. Miller, Shunsuke Kitajima, Rohit Thummalapalli, Benchun Miao, Thanh U. Barbie, Vivek Sivathanu, Joshua Wong, William G. Richards, Raphael Bueno, Charles H. Yoon, Juan Miret, Meenhard Herlyn, Levi A. Garraway, Eliezer M. Van Allen, Gordon J. Freeman, Paul T. Kirschmeier, Jochen H. Lorch, Patrick A. Ott, F. Stephen Hodi, Keith T. Flaherty, Roger D. Kamm, Genevieve M. Boland, Kwok-Kin Wong, David Dornan, Cloud Peter Paweletz, David A. Barbie
Journal: Cancer Discovery
Cancer Discov (2018) 8 (2): 196–215.
https://doi.org/10.1158/2159-8290.CD-17-0833
Published: 04 February 2018
View article titled, <em>Ex Vivo</em> Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
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Includes: Multimedia, Supplementary data
Journal Articles

CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

Jiehui Deng, Eric S. Wang, Russell W. Jenkins, Shuai Li, Ruben Dries, Kathleen Yates, Sandeep Chhabra, Wei Huang, Hongye Liu, Amir R. Aref, Elena Ivanova, Cloud P. Paweletz, Michaela Bowden, Chensheng W. Zhou, Grit S. Herter-Sprie, Jessica A. Sorrentino, John E. Bisi, Patrick H. Lizotte, Ashley A. Merlino, Max M. Quinn, Lauren E. Bufe, Annan Yang, Yanxi Zhang, Hua Zhang, Peng Gao, Ting Chen, Megan E. Cavanaugh, Amanda J. Rode, Eric Haines, Patrick J. Roberts, Jay C. Strum, William G. Richards, Jochen H. Lorch, Sareh Parangi, Viswanath Gunda, Genevieve M. Boland, Raphael Bueno, Sangeetha Palakurthi, Gordon J. Freeman, Jerome Ritz, W. Nicholas Haining, Norman E. Sharpless, Haribabu Arthanari, Geoffrey I. Shapiro, David A. Barbie, Nathanael S. Gray, Kwok-Kin Wong
Journal: Cancer Discovery
Cancer Discov (2018) 8 (2): 216–233.
https://doi.org/10.1158/2159-8290.CD-17-0915
Published: 04 February 2018
View article titled, CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
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Includes: Supplementary data
Journal Articles

Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression

Maria Rusan, Kapsok Li, Yvonne Li, Camilla L. Christensen, Brian J. Abraham, Nicholas Kwiatkowski, Kevin A. Buczkowski, Bruno Bockorny, Ting Chen, Shuai Li, Kevin Rhee, Haikuo Zhang, Wankun Chen, Hideki Terai, Tiffany Tavares, Alan L. Leggett, Tianxia Li, Yichen Wang, Tinghu Zhang, Tae-Jung Kim, Sook-Hee Hong, Neermala Poudel-Neupane, Michael Silkes, Tenny Mudianto, Li Tan, Takeshi Shimamura, Matthew Meyerson, Adam J. Bass, Hideo Watanabe, Nathanael S. Gray, Richard A. Young, Kwok-Kin Wong, Peter S. Hammerman
Journal: Cancer Discovery
Cancer Discov (2018) 8 (1): 59–73.
https://doi.org/10.1158/2159-8290.CD-17-0461
Published: 07 January 2018
View article titled, Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression
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Includes: Supplementary data
Journal Articles

Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer

Dennis O. Adeegbe, Yan Liu, Patrick H. Lizotte, Yusuke Kamihara, Amir R. Aref, Christina Almonte, Ruben Dries, Yuyang Li, Shengwu Liu, Xiaoen Wang, Tiquella Warner-Hatten, Jessica Castrillon, Guo-Cheng Yuan, Neermala Poudel-Neupane, Haikuo Zhang, Jennifer L. Guerriero, Shiwei Han, Mark M. Awad, David A. Barbie, Jerome Ritz, Simon S. Jones, Peter S. Hammerman, James Bradner, Steven N. Quayle, Kwok-Kin Wong
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 852–867.
https://doi.org/10.1158/2159-8290.CD-16-1020
Published: 01 August 2017
View article titled, Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer
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Includes: Supplementary data