1-6 of 6
Kevin M. Haigis
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention

Christian Johnson, Deborah L. Burkhart, Kevin M. Haigis
Journal: Cancer Discovery
Cancer Discov (2022) 12 (4): 913–923.
DOI: https://doi.org/10.1158/2159-8290.CD-22-0035
Published: 01 April 2022
View article
PDF
Journal Articles

MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression

John R.P. Knight, Constantinos Alexandrou, George L. Skalka, Nikola Vlahov, Kathryn Pennel, Leah Officer, Ana Teodosio, Georgios Kanellos, David M. Gay, Sebastian May-Wilson, Ewan M. Smith, Arafath K. Najumudeen, Kathryn Gilroy, Rachel A. Ridgway, Dustin J. Flanagan, Rachael C.L. Smith, Laura McDonald, Craig MacKay, Anne Cheasty, Kerri McArthur, Emma Stanway, Joshua D. Leach, Rene Jackstadt, Joseph A. Waldron, Andrew D. Campbell, Georgios Vlachogiannis, Nicola Valeri, Kevin M. Haigis, Nahum Sonenberg, Christopher G. Proud, Neil P. Jones, Martin E. Swarbrick, Heather J. McKinnon, William J. Faller, John Le Quesne, Joanne Edwards, Anne E. Willis, Martin Bushell, Owen J. Sansom
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (5): 1228–1247.
DOI: https://doi.org/10.1158/2159-8290.CD-20-0652
Published: 01 May 2021
View article
PDF
Includes: Supplementary data
Journal Articles

Tissue-Specific Oncogenic Activity of KRASA146T

Emily J. Poulin, Asim K. Bera, Jia Lu, Yi-Jang Lin, Samantha Dale Strasser, Joao A. Paulo, Tannie Q. Huang, Carolina Morales, Wei Yan, Joshua Cook, Jonathan A. Nowak, Douglas K. Brubaker, Brian A. Joughin, Christian W. Johnson, Rebecca A. DeStefanis, Phaedra C. Ghazi, Sudershan Gondi, Thomas E. Wales, Roxana E. Iacob, Lana Bogdanova, Jessica J. Gierut, Yina Li, John R. Engen, Pedro A. Perez-Mancera, Benjamin S. Braun, Steven P. Gygi, Douglas A. Lauffenburger, Kenneth D. Westover, Kevin M. Haigis
Journal: Cancer Discovery
Cancer Discov (2019) 9 (6): 738–755.
DOI: https://doi.org/10.1158/2159-8290.CD-18-1220
Published: 03 June 2019
View article
PDF
Includes: Supplementary data
Journal Articles

Dominant Role of Oncogene Dosage and Absence of Tumor Suppressor Activity in Nras-Driven Hematopoietic Transformation

Jin Xu, Kevin M. Haigis, Ari J. Firestone, Megan E. McNerney, Qing Li, Elizabeth Davis, Shann-Ching Chen, Joy Nakitandwe, James Downing, Tyler Jacks, Michelle M. Le Beau, Kevin Shannon
Journal: Cancer Discovery
Cancer Discov (2013) 3 (9): 993–1001.
DOI: https://doi.org/10.1158/2159-8290.CD-13-0096
Published: 09 September 2013
View article
PDF
Includes: Supplementary data
Journal Articles

Mutant N-RAS Protects Colorectal Cancer Cells from Stress-Induced Apoptosis and Contributes to Cancer Development and Progression

Yufang Wang, Sérgia Velho, Efsevia Vakiani, Shouyong Peng, Adam J. Bass, Gerald C. Chu, Jessica Gierut, James M. Bugni, Channing J. Der, Mark Philips, David B. Solit, Kevin M. Haigis
Journal: Cancer Discovery
Cancer Discov (2013) 3 (3): 294–307.
DOI: https://doi.org/10.1158/2159-8290.CD-12-0198
Published: 07 March 2013
View article
PDF
Includes: Supplementary data
Journal Articles

Cancers of the Colon and Rectum: Identical or Fraternal Twins?

Theodore S. Hong, Jeffrey W. Clark, Kevin M. Haigis
Journal: Cancer Discovery
Cancer Discov (2012) 2 (2): 117–121.
DOI: https://doi.org/10.1158/2159-8290.CD-11-0315
Published: 12 February 2012
View article
PDF