1-5 of 5
Keith L. Ligon
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers

Kathryn Gunn, Matti Myllykoski, John Z. Cao, Manna Ahmed, Bofu Huang, Betty Rouaisnel, Bill H. Diplas, Michael M. Levitt, Ryan Looper, John G. Doench, Keith L. Ligon, Harley I. Kornblum, Samuel K. McBrayer, Hai Yan, Cihangir Duy, Lucy A. Godley, Peppi Koivunen, Julie-Aurore Losman
Journal: Cancer Discovery
Cancer Discov (2023) 13 (6): 1478–1497.
https://doi.org/10.1158/2159-8290.CD-22-0825
Published: 02 June 2023
View article titled, <em>(R)</em>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <em>IDH</em>-Mutant Cancers
Open the PDF for <em>(R)</em>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <em>IDH</em>-Mutant Cancers in another window
Includes: Supplementary data
Journal Articles

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Eshini Panditharatna, Joana G. Marques, Tingjian Wang, Maria C. Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V. Dharia, Deyao Li, Samantha E. Hoffman, Guillaume Kugener, McKenzie L. Shaw, Hafsa M. Mire, Olivia A. Hack, Joshua M. Dempster, Caleb Lareau, Lingling Dai, Logan H. Sigua, Michael A. Quezada, Ann-Catherine J. Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Federica Piccioni, John G. Doench, David E. Root, Jamie N. Anastas, Kristen L. Jones, Amy Saur Conway, Sylwia Stopka, Michael S. Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P. Jerome, Nathan D. Mathewson, Sirano Dhe-Paganon, Mario L. Suvà, Angel M. Carcaboso, Cinzia Lavarino, Jaume Mora, Quang-De Nguyen, Keith L. Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y.R. Agar, Kimberly Stegmaier, Charles D. Stiles, Michelle Monje, Todd R. Golub, Jun Qi, Mariella G. Filbin
Journal: Cancer Discovery
Cancer Discov (2022) 12 (12): 2880–2905.
https://doi.org/10.1158/2159-8290.CD-21-1491
Published: 02 December 2022
View article titled, BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
Open the PDF for BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma in another window
Includes: Supplementary data
Journal Articles

Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain

Javier Ganz, Eduardo A. Maury, Basheer Becerra, Sara Bizzotto, Ryan N. Doan, Connor J. Kenny, Taehwan Shin, Junho Kim, Zinan Zhou, Keith L. Ligon, Eunjung Alice Lee, Christopher A. Walsh
Journal: Cancer Discovery
Cancer Discov (2022) 12 (1): 172–185.
https://doi.org/10.1158/2159-8290.CD-21-0245
Published: 01 January 2022
View article titled, Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain
Open the PDF for Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain in another window
Includes: Supplementary data
Journal Articles

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Daniel P. Cahill, Amaro Taylor-Weiner, Robert T. Jones, Eliezer M. Van Allen, Michael S. Lawrence, Peleg M. Horowitz, Kristian Cibulskis, Keith L. Ligon, Josep Tabernero, Joan Seoane, Elena Martinez-Saez, William T. Curry, Ian F. Dunn, Sun Ha Paek, Sung-Hye Park, Aaron McKenna, Aaron Chevalier, Mara Rosenberg, Frederick G. Barker, II, Corey M. Gill, Paul Van Hummelen, Aaron R. Thorner, Bruce E. Johnson, Mai P. Hoang, Toni K. Choueiri, Sabina Signoretti, Carrie Sougnez, Michael S. Rabin, Nancy U. Lin, Eric P. Winer, Anat Stemmer-Rachamimov, Matthew Meyerson, Levi Garraway, Stacey Gabriel, Eric S. Lander, Rameen Beroukhim, Tracy T. Batchelor, José Baselga, David N. Louis, Gad Getz, William C. Hahn
Journal: Cancer Discovery
Cancer Discov (2015) 5 (11): 1164–1177.
https://doi.org/10.1158/2159-8290.CD-15-0369
Published: 01 November 2015
View article titled, Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Open the PDF for Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets in another window
Includes: Supplementary data
Journal Articles

EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing

Joshua M. Francis, Cheng-Zhong Zhang, Cecile L. Maire, Joonil Jung, Veronica E. Manzo, Viktor A. Adalsteinsson, Heather Homer, Sam Haidar, Brendan Blumenstiel, Chandra Sekhar Pedamallu, Azra H. Ligon, J. Christopher Love, Matthew Meyerson, Keith L. Ligon
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (8): 956–971.
https://doi.org/10.1158/2159-8290.CD-13-0879
Published: 03 August 2014
View article titled, <em>EGFR</em> Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing
Open the PDF for <em>EGFR</em> Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing in another window
Includes: Supplementary data