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Kathryn C. Arbour
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Journal Articles

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

Jingjing Jiang, Lingyan Jiang, Benjamin J. Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P. Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J. Rosen, Yevgeniy Gindin, Bianca J. Lee, James W. Evans, Stephanie Chang, Zhican Wang, Kyle J. Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C.A. Tomlinson, Jason K. Yano, John E. Knox, Elsa Quintana, Andrew J. Aguirre, Kathryn C. Arbour, Abby Reed, W. Clay Gustafson, Adrian L. Gill, Elena S. Koltun, David Wildes, Jacqueline A.M. Smith, Zhengping Wang, Mallika Singh
Journal: Cancer Discovery
Cancer Discov (2024) 14 (6): 994–1017.
https://doi.org/10.1158/2159-8290.CD-24-0027
Published: 03 June 2024
View article titled, Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers
Open the PDF for Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers in another window
Includes: Supplementary data
Journal Articles

MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer

Lars D. Engstrom, Ruth Aranda, Laura Waters, Krystal Moya, Vickie Bowcut, Laura Vegar, David Trinh, Allan Hebbert, Christopher R. Smith, Svitlana Kulyk, J. David Lawson, Leo He, Laura D. Hover, Julio Fernandez-Banet, Jill Hallin, Darin Vanderpool, David M. Briere, Alice Blaj, Matthew A. Marx, Jordi Rodon, Michael Offin, Kathryn C. Arbour, Melissa L. Johnson, David J. Kwiatkowski, Pasi A. Jänne, Candace L. Haddox, Kyriakos P. Papadopoulos, Jason T. Henry, Konstantinos Leventakos, James G. Christensen, Ronald Shazer, Peter Olson
Journal: Cancer Discovery
Cancer Discov (2023) 13 (11): 2412–2431.
https://doi.org/10.1158/2159-8290.CD-23-0669
Published: 01 November 2023
View article titled, MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with <em>MTAP</em>-Deleted Cancer
Open the PDF for MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with <em>MTAP</em>-Deleted Cancer in another window
Includes: Supplementary data
Journal Articles

Deep Learning to Estimate RECIST in Patients with NSCLC Treated with PD-1 Blockade

Kathryn C. Arbour, Anh Tuan Luu, Jia Luo, Hira Rizvi, Andrew J. Plodkowski, Mustafa Sakhi, Kevin B. Huang, Subba R. Digumarthy, Michelle S. Ginsberg, Jeffrey Girshman, Mark G. Kris, Gregory J. Riely, Adam Yala, Justin F. Gainor, Regina Barzilay, Matthew D. Hellmann
Journal: Cancer Discovery
Cancer Discov (2021) 11 (1): 59–67.
https://doi.org/10.1158/2159-8290.CD-20-0419
Published: 06 January 2021
View article titled, Deep Learning to Estimate RECIST in Patients with NSCLC Treated with PD-1 Blockade
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Includes: Supplementary data