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Katerina Politi
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Journal Articles

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth

Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S. Kuna, Kacie A. Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M. Kwong, Stellar Levy, Anna-Maria Globig, Matthew M. Nobari, George Z. Cheng, Sandra L. Leibel, Robert J. Homer, Reuben J. Shaw, Christian M. Metallo, Katerina Politi, Susan M. Kaech
Journal: Cancer Discovery
Cancer Discov (2024) 14 (3): 524–545.
https://doi.org/10.1158/2159-8290.CD-23-0434
Published: 01 March 2024
View article titled, EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
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Includes: Supplementary data
Journal Articles

Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo

Giorgia Foggetti, Chuan Li, Hongchen Cai, Jessica A. Hellyer, Wen-Yang Lin, Deborah Ayeni, Katherine Hastings, Jungmin Choi, Anna Wurtz, Laura Andrejka, Dylan G. Maghini, Nicholas Rashleigh, Stellar Levy, Robert Homer, Scott N. Gettinger, Maximilian Diehn, Heather A. Wakelee, Dmitri A. Petrov, Monte M. Winslow, Katerina Politi
Journal: Cancer Discovery
Cancer Discov (2021) 11 (7): 1736–1753.
https://doi.org/10.1158/2159-8290.CD-20-1385
Published: 01 July 2021
View article titled, Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response <em>In Vivo</em>
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Includes: Supplementary data
Journal Articles

ERBB Signaling Interrupted: Targeting Ligand-Induced Pathway Activation

Frederick H. Wilson, Katerina Politi
Journal: Cancer Discovery
Cancer Discov (2018) 8 (6): 676–678.
https://doi.org/10.1158/2159-8290.CD-18-0368
Published: 31 May 2018
View article titled, ERBB Signaling Interrupted: Targeting Ligand-Induced Pathway Activation
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Journal Articles

Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer

Scott Gettinger, Jungmin Choi, Katherine Hastings, Anna Truini, Ila Datar, Ryan Sowell, Anna Wurtz, Weilai Dong, Guoping Cai, Mary Ann Melnick, Victor Y. Du, Joseph Schlessinger, Sarah B. Goldberg, Anne Chiang, Miguel F. Sanmamed, Ignacio Melero, Jackeline Agorreta, Luis M. Montuenga, Richard Lifton, Soldano Ferrone, Paula Kavathas, David L. Rimm, Susan M. Kaech, Kurt Schalper, Roy S. Herbst, Katerina Politi
Journal: Cancer Discovery
Cancer Discov (2017) 7 (12): 1420–1435.
https://doi.org/10.1158/2159-8290.CD-17-0593
Published: 04 December 2017
View article titled, Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
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Includes: Supplementary data
Journal Articles

Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor–Driven Lung Adenocarcinoma

Tapan K. Maity, Abhilash Venugopalan, Ilona Linnoila, Constance M. Cultraro, Andreas Giannakou, Roxanne Nemati, Xu Zhang, Joshua D. Webster, Daniel Ritt, Sarani Ghosal, Heinz Hoschuetzky, R. Mark Simpson, Romi Biswas, Katerina Politi, Deborah K. Morrison, Harold E. Varmus, Udayan Guha
Journal: Cancer Discovery
Cancer Discov (2015) 5 (5): 534–549.
https://doi.org/10.1158/2159-8290.CD-14-0750
Published: 03 May 2015
View article titled, Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor–Driven Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Reduced NF1 Expression Confers Resistance to EGFR Inhibition in Lung Cancer

Elza C. de Bruin, Catherine Cowell, Patricia H. Warne, Ming Jiang, Rebecca E. Saunders, Mary Ann Melnick, Scott Gettinger, Zenta Walther, Anna Wurtz, Guus J. Heynen, Daniëlle A.M. Heideman, Javier Gómez-Román, Almudena García-Castaño, Yixuan Gong, Marc Ladanyi, Harold Varmus, René Bernards, Egbert F. Smit, Katerina Politi, Julian Downward
Journal: Cancer Discovery
Cancer Discov (2014) 4 (5): 606–619.
https://doi.org/10.1158/2159-8290.CD-13-0741
Published: 01 May 2014
View article titled, Reduced <em>NF1</em> Expression Confers Resistance to EGFR Inhibition in Lung Cancer
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Includes: Supplementary data
Journal Articles

MYCxing It Up with FGFR1 in Squamous Cell Lung Cancer

William Lockwood, Katerina Politi
Journal: Cancer Discovery
Cancer Discov (2014) 4 (2): 152–154.
https://doi.org/10.1158/2159-8290.CD-13-1049
Published: 04 February 2014
View article titled, MYCxing It Up with FGFR1 in Squamous Cell Lung Cancer
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Journal Articles

Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M

Ho-June Lee, Gabriele Schaefer, Timothy P. Heffron, Lily Shao, Xiaofen Ye, Steve Sideris, Shiva Malek, Emily Chan, Mark Merchant, Hank La, Savita Ubhayakar, Robert L. Yauch, Valentina Pirazzoli, Katerina Politi, Jeff Settleman
Journal: Cancer Discovery
Cancer Discov (2013) 3 (2): 168–181.
https://doi.org/10.1158/2159-8290.CD-12-0357
Published: 10 February 2013
View article titled, Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M
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Includes: Supplementary data
Journal Articles

HER2 Amplification: A Potential Mechanism of Acquired Resistance to EGFR Inhibition in EGFR-Mutant Lung Cancers That Lack the Second-Site EGFRT790M Mutation

Ken Takezawa, Valentina Pirazzoli, Maria E. Arcila, Caroline A. Nebhan, Xiaoling Song, Elisa de Stanchina, Kadoaki Ohashi, Yelena Y. Janjigian, Paula J. Spitzler, Mary Ann Melnick, Greg J. Riely, Mark G. Kris, Vincent A. Miller, Marc Ladanyi, Katerina Politi, William Pao
Journal: Cancer Discovery
Cancer Discov (2012) 2 (10): 922–933.
https://doi.org/10.1158/2159-8290.CD-12-0108
Published: 14 October 2012
View article titled, <em>HER2</em> Amplification: A Potential Mechanism of Acquired Resistance to EGFR Inhibition in <em>EGFR</em>-Mutant Lung Cancers That Lack the Second-Site <em>EGFR</em><sup>T790M</sup> Mutation
Open the PDF for <em>HER2</em> Amplification: A Potential Mechanism of Acquired Resistance to EGFR Inhibition in <em>EGFR</em>-Mutant Lung Cancers That Lack the Second-Site <em>EGFR</em><sup>T790M</sup> Mutation in another window
Includes: Supplementary data