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Journal Articles

Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally

Available to Purchase
Javier Carmona, Elena Chavarria, Kate Donoghue, Christina von Gertten, Petra Oberrauch, Emma Pailler, Giovanni Scoazec, Ruud Weijer, Judith Balmaña, Irene Brana, Cinzia Brunelli, Suzette Delaloge, Marc Deloger, Pierre Delpy, Ingemar Ernberg, Rebecca C. Fitzgerald, Elena Garralda, Martin Lablans, Janne Lëhtio, Carlos Lopez, Maialen Fernández, Rosalba Miceli, Paolo Nuciforo, Raquel Perez-Lopez, Elena Provenzano, Marjanka K. Schmidt, Cesar Serrano, Neeltje Steeghs, David Tamborero, Valtteri Wirta, Richard D. Baird, Karen Barker, Fabrice Barlesi, Michael Baumann, Jonas Bergh, Filippo de Braud, Karim Fizazi, Stefan Fröhling, Alejandro Piris-Giménez, Kenneth Seamon, Michiel S. Van der Heijden, Wilbert Zwart, Josep Tabernero
Journal: Cancer Discovery
Cancer Discov (2024) 14 (7): 1147–1153.
https://doi.org/10.1158/2159-8290.CD-24-0377
Published: 01 July 2024
View articletitled, Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally
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Journal Articles

UNCAN.eu: Toward a European Federated Cancer Research Data Hub

Open Access
Michael Boutros, Michael Baumann, Anna Bigas, Linda Chaabane, Julien Guérin, Jens K. Habermann, Aurélien Jobard, Pier Giuseppe Pelicci, Oliver Stegle, Giovanni Tonon, Alfonso Valencia, Eva C. Winkler, Patricia Blanc, Ruggero De Maria, Rene H. Medema, Peter Nagy, Josep Tabernero, Eric Solary
Journal: Cancer Discovery
Cancer Discov (2024) 14 (1): 30–35.
https://doi.org/10.1158/2159-8290.CD-23-1111
Published: 12 January 2024
View articletitled, UNCAN.eu: Toward a European Federated Cancer Research Data Hub
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Journal Articles

Early-Stage Breast Cancer Detection in Breast Milk

Open Access
Cristina Saura, Carolina Ortiz, Judit Matito, Enrique J. Arenas, Anna Suñol, Ágatha Martín, Octavi Córdoba, Alex Martínez-Sabadell, Itziar García-Ruiz, Ignacio Miranda, Clara Morales-Comas, Estela Carrasco, Cristina Viaplana, Vicente Peg, Paolo Nuciforo, Neus Bayó-Puxan, Alberto Gonzalez-Medina, Josep M. Miquel, Marina Gómez-Rey, Guillermo Villacampa, Silvia Arévalo, Martín Espinosa-Bravo, Judith Balmaña, Rodrigo Dienstmann, Joaquin Arribas, Josep Tabernero, Ana Vivancos, Miriam Sansó
Journal: Cancer Discovery
Cancer Discov (2023) 13 (10): 2180–2191.
https://doi.org/10.1158/2159-8290.CD-22-1340
Published: 05 October 2023
View articletitled, Early-Stage Breast Cancer Detection in Breast Milk
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Includes: Supplementary data
Journal Articles

UNCAN.eu, a European Initiative to UNderstand CANcer

Available to Purchase
Eric Solary, Patricia Blanc, Michael Boutros, Charis Girvalaki, Franco Locatelli, Rene H. Medema, Péter Nagy, Josep Tabernero
Journal: Cancer Discovery
Cancer Discov (2022) 12 (11): 2504–2508.
https://doi.org/10.1158/2159-8290.CD-22-0970
Published: 02 November 2022
View articletitled, UNCAN.eu, a European Initiative to UNderstand CANcer
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Journal Articles

José “Pepe” Baselga, MD, PhD: In Memoriam (1959–2021)

Free
Josep Tabernero, David M. Hyman, Jean-Charles Soria
Journal: Cancer Discovery
Cancer Discov (2021) 11 (7): 1614–1616.
https://doi.org/10.1158/2159-8290.CD-21-0458
Published: 01 July 2021
View articletitled, José “Pepe” Baselga, MD, PhD: In Memoriam (1959–2021)
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Journal Articles

Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer

Free
David J. Pinato, Alberto Zambelli, Juan Aguilar-Company, Mark Bower, Christopher C.T. Sng, Ramon Salazar, Alexia Bertuzzi, Joan Brunet, Ricard Mesia, Elia Seguí, Federica Biello, Daniele Generali, Salvatore Grisanti, Gianpiero Rizzo, Michela Libertini, Antonio Maconi, Nadia Harbeck, Bruno Vincenzi, Rossella Bertulli, Diego Ottaviani, Anna Carbó, Riccardo Bruna, Sarah Benafif, Andrea Marrari, Rachel Wuerstlein, M. Carmen Carmona-Garcia, Neha Chopra, Carlo Tondini, Oriol Mirallas, Valeria Tovazzi, Marta Betti, Salvatore Provenzano, Vittoria Fotia, Claudia Andrea Cruz, Alessia Dalla Pria, Francesca D'Avanzo, Joanne S. Evans, Nadia Saoudi-Gonzalez, Eudald Felip, Myria Galazi, Isabel Garcia-Fructuoso, Alvin J.X. Lee, Thomas Newsom-Davis, Andrea Patriarca, David García-Illescas, Roxana Reyes, Palma Dileo, Rachel Sharkey, Yien Ning Sophia Wong, Daniela Ferrante, Javier Marco-Hernández, Anna Sureda, Clara Maluquer, Isabel Ruiz-Camps, Gianluca Gaidano, Lorenza Rimassa, Lorenzo Chiudinelli, Macarena Izuzquiza, Alba Cabirta, Michela Franchi, Armando Santoro, Aleix Prat, Josep Tabernero, Alessandra Gennari, Gian Carlo Avanzi, Mattia Bellan, Luigi Mario Castello, Maria Martinez, Meritxell Mollà, Mario Pirisi, Lorenza Scotti, Judith Swallow
Journal: Cancer Discovery
Cancer Discov (2020) 10 (10): 1465–1474.
https://doi.org/10.1158/2159-8290.CD-20-0773
Published: 01 October 2020
View articletitled, Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer
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Includes: Supplementary data
Journal Articles

Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAFV600E-Mutant Colorectal Cancer

Free
Ryan B. Corcoran, Thierry André, Chloe E. Atreya, Jan H.M. Schellens, Takayuki Yoshino, Johanna C. Bendell, Antoine Hollebecque, Autumn J. McRee, Salvatore Siena, Gary Middleton, Kei Muro, Michael S. Gordon, Josep Tabernero, Rona Yaeger, Peter J. O'Dwyer, Yves Humblet, Filip De Vos, A. Scott Jung, Jan C. Brase, Savina Jaeger, Severine Bettinger, Bijoyesh Mookerjee, Fatima Rangwala, Eric Van Cutsem
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (4): 428–443.
https://doi.org/10.1158/2159-8290.CD-17-1226
Published: 01 April 2018
View articletitled, Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAFV600E-Mutant Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Improving the Armamentarium of PI3K Inhibitors with Isoform-Selective Agents: A New Light in the Darkness

Free
Jordi Rodon, Josep Tabernero
Journal: Cancer Discovery
Cancer Discov (2017) 7 (7): 666–669.
https://doi.org/10.1158/2159-8290.CD-17-0500
Published: 05 July 2017
View articletitled, Improving the Armamentarium of PI3K Inhibitors with Isoform-Selective Agents: A New Light in the Darkness
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Journal Articles

A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic BRAF-Mutant Colorectal Cancer

Free
Robin M.J.M. van Geel, Josep Tabernero, Elena Elez, Johanna C. Bendell, Anna Spreafico, Martin Schuler, Takayuki Yoshino, Jean-Pierre Delord, Yasuhide Yamada, Martijn P. Lolkema, Jason E. Faris, Ferry A.L.M. Eskens, Sunil Sharma, Rona Yaeger, Heinz-Josef Lenz, Zev A. Wainberg, Emin Avsar, Arkendu Chatterjee, Savina Jaeger, Eugene Tan, Kati Maharry, Tim Demuth, Jan H.M. Schellens
Journal: Cancer Discovery
Cancer Discov (2017) 7 (6): 610–619.
https://doi.org/10.1158/2159-8290.CD-16-0795
Published: 01 June 2017
View articletitled, A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic BRAF-Mutant Colorectal Cancer
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Includes: Supplementary data
Journal Articles

A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors

Free
Cristina Saura, Desamparados Roda, Susana Roselló, Mafalda Oliveira, Teresa Macarulla, José Alejandro Pérez-Fidalgo, Rafael Morales-Barrera, Juan Manuel Sanchis-García, Luna Musib, Nageshwar Budha, Jin Zhu, Michelle Nannini, Wai Y. Chan, Sandra M. Sanabria Bohórquez, Raymond D. Meng, Kui Lin, Yibing Yan, Premal Patel, José Baselga, Josep Tabernero, Andrés Cervantes
Journal: Cancer Discovery
Cancer Discov (2017) 7 (1): 102–113.
https://doi.org/10.1158/2159-8290.CD-16-0512
Published: 05 January 2017
View articletitled, A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors
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Includes: Supplementary data
Journal Articles

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

Free
Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Daniel P. Cahill, Amaro Taylor-Weiner, Robert T. Jones, Eliezer M. Van Allen, Michael S. Lawrence, Peleg M. Horowitz, Kristian Cibulskis, Keith L. Ligon, Josep Tabernero, Joan Seoane, Elena Martinez-Saez, William T. Curry, Ian F. Dunn, Sun Ha Paek, Sung-Hye Park, Aaron McKenna, Aaron Chevalier, Mara Rosenberg, Frederick G. Barker, II, Corey M. Gill, Paul Van Hummelen, Aaron R. Thorner, Bruce E. Johnson, Mai P. Hoang, Toni K. Choueiri, Sabina Signoretti, Carrie Sougnez, Michael S. Rabin, Nancy U. Lin, Eric P. Winer, Anat Stemmer-Rachamimov, Matthew Meyerson, Levi Garraway, Stacey Gabriel, Eric S. Lander, Rameen Beroukhim, Tracy T. Batchelor, José Baselga, David N. Louis, Gad Getz, William C. Hahn
Journal: Cancer Discovery
Cancer Discov (2015) 5 (11): 1164–1177.
https://doi.org/10.1158/2159-8290.CD-15-0369
Published: 01 November 2015
View articletitled, Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
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Includes: Supplementary data
Journal Articles

Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer

Free
Rodrigo Dienstmann, Amita Patnaik, Rocio Garcia-Carbonero, Andrés Cervantes, Marta Benavent, Susana Roselló, Bastiaan B.J. Tops, Rachel S. van der Post, Guillem Argilés, Niels J.Ø. Skartved, Ulla H. Hansen, Rikke Hald, Mikkel W. Pedersen, Michael Kragh, Ivan D. Horak, Stephan Braun, Eric Van Cutsem, Anthony W. Tolcher, Josep Tabernero
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (6): 598–609.
https://doi.org/10.1158/2159-8290.CD-14-1432
Published: 01 June 2015
View articletitled, Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Molecular Dissection of Microsatellite Instable Colorectal Cancer

Free
Eduardo Vilar, Josep Tabernero
Journal: Cancer Discovery
Cancer Discov (2013) 3 (5): 502–511.
https://doi.org/10.1158/2159-8290.CD-12-0471
Published: 08 May 2013
View articletitled, Molecular Dissection of Microsatellite Instable Colorectal Cancer
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Journal Articles

First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

Free
Josep Tabernero, Geoffrey I. Shapiro, Patricia M. LoRusso, Andres Cervantes, Gary K. Schwartz, Glen J. Weiss, Luis Paz-Ares, Daniel C. Cho, Jeffrey R. Infante, Maria Alsina, Mrinal M. Gounder, Rick Falzone, Jamie Harrop, Amy C. Seila White, Iva Toudjarska, David Bumcrot, Rachel E. Meyers, Gregory Hinkle, Nenad Svrzikapa, Renta M. Hutabarat, Valerie A. Clausen, Jeffrey Cehelsky, Saraswathy V. Nochur, Christina Gamba-Vitalo, Akshay K. Vaishnaw, Dinah W.Y. Sah, Jared A. Gollob, Howard A. Burris, III
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (4): 406–417.
https://doi.org/10.1158/2159-8290.CD-12-0429
Published: 10 April 2013
View articletitled, First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement
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Includes: Supplementary data
Journal Articles

A Shining Light in the Darkness for the Treatment of Pancreatic Neuroendocrine Tumors

Free
Jaume Capdevila, Josep Tabernero
Journal: Cancer Discovery
Cancer Discov (2011) 1 (3): 213–221.
https://doi.org/10.1158/2159-8290.CD-11-0151
Published: 15 August 2011
View articletitled, A Shining Light in the Darkness for the Treatment of Pancreatic Neuroendocrine Tumors
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