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John M. Maris
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Journal Articles

Identification and Characterization of Chemotherapy-Resistant High-Risk Neuroblastoma Persister Cells

Open Access
Liron D. Grossmann, Chia-Hui Chen, Yasin Uzun, Anusha Thadi, Adam J. Wolpaw, Kevin Louault, Yael Goldstein, Lea F. Surrey, Daniel Martinez, Matteo Calafatti, Mark Gerelus, Peng Gao, Lobin Lee, Khushbu Patel, Rebecca S. Kaufman, Guy Shani, Alvin Farrel, Sharon Moshitch-Moshkovitz, Paris Grimaldi, Matthew Shapiro, Nathan M. Kendsersky, Jarrett M. Lindsay, Colleen E. Casey, Kateryna Krytska, Laura Scolaro, Matthew Tsang, David Groff, Smita Matkar, Josh R. Kalna, Emily Mycek, Jayne McDevitt, Erin Runbeck, Tasleema Patel, Kathrin M. Bernt, Shahab Asgharzadeh, Yves A. DeClerck, Yael P. Mossé, Kai Tan, John M. Maris
Journal: Cancer Discovery
Cancer Discov (2024) 14 (12): 2387–2406.
https://doi.org/10.1158/2159-8290.CD-24-0046
Published: 02 December 2024
View articletitled, Identification and Characterization of Chemotherapy-Resistant High-Risk Neuroblastoma Persister Cells
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Includes: Supplementary data
Journal Articles

The Virtual Child

Available to Purchase
Richard J. Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E. Bronner, Matthew Burridge, Henrick Clausing, Harry Clifford, Tracey Danaher, Laura K. Donovan, Jarno Drost, Alexander M.M. Eggermont, Chris Emerson, Mona G. Flores, Petra Hamerlik, Nada Jabado, Andrew Jones, Henrick Kaessmann, Claudia L. Kleinman, Marcel Kool, Lena M. Kutscher, Gavin Lindberg, Emily Linnane, John C. Marioni, John M. Maris, Michelle Monje, Alexandra Macaskill, Steven Niederer, Paul A. Northcott, Elizabeth Peeters, Willemijn Plieger-van Solkema, Liane Preußner, Anne C. Rios, Karsten Rippe, Peter Sandford, Nikolaos G. Sgourakis, Adam Shlien, Pete Smith, Karin Straathof, Patrick J. Sullivan, Mario L. Suvà, Michael D. Taylor, Emma Thompson, Roser Vento-Tormo, Brandon J. Wainwright, Robert J. Wechsler-Reya, Frank Westermann, Shannon Winslade, Bissan Al-Lazikani, Stefan M. Pfister
Journal: Cancer Discovery
Cancer Discov (2024) 14 (4): 663–668.
https://doi.org/10.1158/2159-8290.CD-23-1500
Published: 04 April 2024
View articletitled, The Virtual Child
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Journal Articles

Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma

Free
Kristopher R. Bosse, Anna Maria Giudice, Maria V. Lane, Brendan McIntyre, Patrick M. Schürch, Guillem Pascual-Pasto, Samantha N. Buongervino, Sriyaa Suresh, Alana Fitzsimmons, Adam Hyman, Maria Gemino-Borromeo, Jennifer Saggio, Esther R. Berko, Alexander A. Daniels, Jennifer Stundon, Megan Friedrichsen, Xin Liu, Matthew L. Margolis, Marilyn M. Li, Marni Brisson Tierno, Geoffrey R. Oxnard, John M. Maris, Yael P. Mossé
Journal: Cancer Discovery
Cancer Discov (2022) 12 (12): 2800–2819.
https://doi.org/10.1158/2159-8290.CD-22-0287
Published: 02 December 2022
View articletitled, Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma
Open the PDF for Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition

Available to Purchase
Brittany B. Campbell, Melissa A. Galati, Simone C. Stone, Alexandra N. Riemenschneider, Melissa Edwards, Sumedha Sudhaman, Robert Siddaway, Martin Komosa, Nuno M. Nunes, Liana Nobre, A. Sorana Morrissy, Matthew Zatzman, Michal Zapotocky, Lazar Joksimovic, Sangeetha N. Kalimuthu, David Samuel, Gary Mason, Eric Bouffet, Daniel A. Morgenstern, Melyssa Aronson, Carol Durno, David Malkin, John M. Maris, Michael D. Taylor, Adam Shlien, Trevor J. Pugh, Pamela S. Ohashi, Cynthia E. Hawkins, Uri Tabori
Journal: Cancer Discovery
Cancer Discov (2021) 11 (6): 1454–1467.
https://doi.org/10.1158/2159-8290.CD-20-1050
Published: 01 June 2021
View articletitled, Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition
Open the PDF for Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition in another window
Includes: Supplementary data
Journal Articles

Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

Available to Purchase
Presha Rajbhandari, Gonzalo Lopez, Claudia Capdevila, Beatrice Salvatori, Jiyang Yu, Ruth Rodriguez-Barrueco, Daniel Martinez, Mark Yarmarkovich, Nina Weichert-Leahey, Brian J. Abraham, Mariano J. Alvarez, Archana Iyer, Jo Lynne Harenza, Derek Oldridge, Katleen De Preter, Jan Koster, Shahab Asgharzadeh, Robert C. Seeger, Jun S. Wei, Javed Khan, Jo Vandesompele, Pieter Mestdagh, Rogier Versteeg, A. Thomas Look, Richard A. Young, Antonio Iavarone, Anna Lasorella, Jose M. Silva, John M. Maris, Andrea Califano
Journal: Cancer Discovery
Cancer Discov (2018) 8 (5): 582–599.
https://doi.org/10.1158/2159-8290.CD-16-0861
Published: 30 April 2018
View articletitled, Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma
Open the PDF for Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

Free
Elena Sotillo, David M. Barrett, Kathryn L. Black, Asen Bagashev, Derek Oldridge, Glendon Wu, Robyn Sussman, Claudia Lanauze, Marco Ruella, Matthew R. Gazzara, Nicole M. Martinez, Colleen T. Harrington, Elaine Y. Chung, Jessica Perazzelli, Ted J. Hofmann, Shannon L. Maude, Pichai Raman, Alejandro Barrera, Saar Gill, Simon F. Lacey, Jan J. Melenhorst, David Allman, Elad Jacoby, Terry Fry, Crystal Mackall, Yoseph Barash, Kristen W. Lynch, John M. Maris, Stephan A. Grupp, Andrei Thomas-Tikhonenko
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (12): 1282–1295.
https://doi.org/10.1158/2159-8290.CD-15-1020
Published: 03 December 2015
View articletitled, Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
Open the PDF for Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Targeting MYCN: A Good BET for Improving Neuroblastoma Therapy?

Available to Purchase
Robert W. Schnepp, John M. Maris
Journal: Cancer Discovery
Cancer Discov (2013) 3 (3): 255–257.
https://doi.org/10.1158/2159-8290.CD-13-0018
Published: 07 March 2013
View articletitled, Targeting MYCN: A Good BET for Improving Neuroblastoma Therapy?
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