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Journal Articles

T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study

Available to Purchase
Justin F. Gainor, Manish R. Patel, Jeffrey S. Weber, Martin Gutierrez, Julie E. Bauman, Jeffrey M. Clarke, Ricklie Julian, Aaron J. Scott, Jessica L. Geiger, Kedar Kirtane, Celine Robert-Tissot, Brandon Coder, Moomal Tasneem, Jing Sun, Wei Zheng, Lauren Gerbereux, Andressa Laino, Filippos Porichis, Jack Russella Pollard, Peijie Hou, Vasudha Sehgal, Xing Chen, Manju Morrissey, Hikmat N. Daghestani, Igor Feldman, Lakshmi Srinivasan, Joshua P. Frederick, Michelle Brown, Praveen Aanur, Robert Meehan, Howard A. Burris, III
Journal: Cancer Discovery
Cancer Discov (2024) 14 (11): 2209–2223.
https://doi.org/10.1158/2159-8290.CD-24-0158
Published: 01 November 2024
View article titled, T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study
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Includes: Supplementary data
Journal Articles

Detecting Liver Cancer Using Cell-Free DNA Fragmentomes

Open Access
Zachariah H. Foda, Akshaya V. Annapragada, Kavya Boyapati, Daniel C. Bruhm, Nicholas A. Vulpescu, Jamie E. Medina, Dimitrios Mathios, Stephen Cristiano, Noushin Niknafs, Harry T. Luu, Michael G. Goggins, Robert A. Anders, Jing Sun, Shruti H. Meta, David L. Thomas, Gregory D. Kirk, Vilmos Adleff, Jillian Phallen, Robert B. Scharpf, Amy K. Kim, Victor E. Velculescu
Journal: Cancer Discovery
Cancer Discov (2023) 13 (3): 616–631.
https://doi.org/10.1158/2159-8290.CD-22-0659
Published: 01 March 2023
View article titled, Detecting Liver Cancer Using Cell-Free DNA Fragmentomes
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Includes: Supplementary data
Journal Articles

AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer

Free
Darren A.E. Cross, Susan E. Ashton, Serban Ghiorghiu, Cath Eberlein, Caroline A. Nebhan, Paula J. Spitzler, Jonathon P. Orme, M. Raymond V. Finlay, Richard A. Ward, Martine J. Mellor, Gareth Hughes, Amar Rahi, Vivien N. Jacobs, Monica Red Brewer, Eiki Ichihara, Jing Sun, Hailing Jin, Peter Ballard, Katherine Al-Kadhimi, Rachel Rowlinson, Teresa Klinowska, Graham H.P. Richmond, Mireille Cantarini, Dong-Wan Kim, Malcolm R. Ranson, William Pao
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (9): 1046–1061.
https://doi.org/10.1158/2159-8290.CD-14-0337
Published: 01 September 2014
View article titled, AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer
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Includes: Supplementary data
Journal Articles

Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC

Free
Annette O. Walter, Robert Tjin Tham Sjin, Henry J. Haringsma, Kadoaki Ohashi, Jing Sun, Kwangho Lee, Aleksandr Dubrovskiy, Matthew Labenski, Zhendong Zhu, Zhigang Wang, Michael Sheets, Thia St Martin, Russell Karp, Dan van Kalken, Prasoon Chaturvedi, Deqiang Niu, Mariana Nacht, Russell C. Petter, William Westlin, Kevin Lin, Sarah Jaw-Tsai, Mitch Raponi, Terry Van Dyke, Jeff Etter, Zoe Weaver, William Pao, Juswinder Singh, Andrew D. Simmons, Thomas C. Harding, Andrew Allen
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (12): 1404–1415.
https://doi.org/10.1158/2159-8290.CD-13-0314
Published: 10 December 2013
View article titled, Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC
Open the PDF for Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC in another window
Includes: Supplementary data