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Jacob M. Rowe
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Journal Articles

Intracellular Cholesterol Pools Regulate Oncogenic Signaling and Epigenetic Circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia

Marissa Rashkovan, Robert Albero, Francesca Gianni, Pablo Perez-Duran, Hannah I. Miller, Adam L. Mackey, Elisabeth M. Paietta, Martin S. Tallman, Jacob M. Rowe, Mark R. Litzow, Peter H. Wiernik, Selina Luger, Maria Luisa Sulis, Rajesh K. Soni, Adolfo A. Ferrando
Journal: Cancer Discovery
Cancer Discov (2022) 12 (3): 856–871.
https://doi.org/10.1158/2159-8290.CD-21-0551
Published: 08 March 2022
View article titled, Intracellular Cholesterol Pools Regulate Oncogenic Signaling and Epigenetic Circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
Open the PDF for Intracellular Cholesterol Pools Regulate Oncogenic Signaling and Epigenetic Circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia

Lindsey E. Montefiori, Sonja Bendig, Zhaohui Gu, Xiaolong Chen, Petri Pölönen, Xiaotu Ma, Alex Murison, Andy Zeng, Laura Garcia-Prat, Kirsten Dickerson, Ilaria Iacobucci, Sherif Abdelhamed, Ryan Hiltenbrand, Paul E. Mead, Cyrus M. Mehr, Beisi Xu, Zhongshan Cheng, Ti-Cheng Chang, Tamara Westover, Jing Ma, Anna Stengel, Shunsuke Kimura, Chunxu Qu, Marcus B. Valentine, Marissa Rashkovan, Selina Luger, Mark R. Litzow, Jacob M. Rowe, Monique L. den Boer, Victoria Wang, Jun Yin, Steven M. Kornblau, Stephen P. Hunger, Mignon L. Loh, Ching-Hon Pui, Wenjian Yang, Kristine R. Crews, Kathryn G. Roberts, Jun J. Yang, Mary V. Relling, William E. Evans, Wendy Stock, Elisabeth M. Paietta, Adolfo A. Ferrando, Jinghui Zhang, Wolfgang Kern, Torsten Haferlach, Gang Wu, John E. Dick, Jeffery M. Klco, Claudia Haferlach, Charles G. Mullighan
Journal: Cancer Discovery
Cancer Discov (2021) 11 (11): 2846–2867.
https://doi.org/10.1158/2159-8290.CD-21-0145
Published: 01 November 2021
View article titled, Enhancer Hijacking Drives Oncogenic <em>BCL11B</em> Expression in Lineage-Ambiguous Stem Cell Leukemia
Open the PDF for Enhancer Hijacking Drives Oncogenic <em>BCL11B</em> Expression in Lineage-Ambiguous Stem Cell Leukemia in another window
Includes: Supplementary data
Journal Articles

Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia

Huimin Geng, Sarah Brennan, Thomas A. Milne, Wei-Yi Chen, Yushan Li, Christian Hurtz, Soo-Mi Kweon, Lynette Zickl, Seyedmehdi Shojaee, Donna Neuberg, Chuanxin Huang, Debabrata Biswas, Yuan Xin, Janis Racevskis, Rhett P. Ketterling, Selina M. Luger, Hillard Lazarus, Martin S. Tallman, Jacob M. Rowe, Mark R. Litzow, Monica L. Guzman, C. David Allis, Robert G. Roeder, Markus Müschen, Elisabeth Paietta, Olivier Elemento, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2012) 2 (11): 1004–1023.
https://doi.org/10.1158/2159-8290.CD-12-0208
Published: 11 November 2012
View article titled, Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia
Open the PDF for Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data