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Ingo K. Mellinghoff
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Journal Articles

Moving Spatially Resolved Multiplexed Protein Profiling toward Clinical Oncology

Maryam Pourmaleki, Nicholas D. Socci, Travis J. Hollmann, Ingo K. Mellinghoff
Journal: Cancer Discovery
Cancer Discov (2023) 13 (4): 824–828.
https://doi.org/10.1158/2159-8290.CD-22-1015
Published: 03 April 2023
View article titled, Moving Spatially Resolved Multiplexed Protein Profiling toward Clinical Oncology
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Includes: Supplementary data
Journal Articles

Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition

James J. Harding, Maeve A. Lowery, Alan H. Shih, Juan M. Schvartzman, Shengqi Hou, Christopher Famulare, Minal Patel, Mikhail Roshal, Richard K. Do, Ahmet Zehir, Daoqi You, S. Duygu Selcuklu, Agnes Viale, Martin S. Tallman, David M. Hyman, Ed Reznik, Lydia W.S. Finley, Elli Papaemmanuil, Alessandra Tosolini, Mark G. Frattini, Kyle J. MacBeth, Guowen Liu, Bin Fan, Sung Choe, Bin Wu, Yelena Y. Janjigian, Ingo K. Mellinghoff, Luis A. Diaz, Ross L. Levine, Ghassan K. Abou-Alfa, Eytan M. Stein, Andrew M. Intlekofer
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (12): 1540–1547.
https://doi.org/10.1158/2159-8290.CD-18-0877
Published: 03 December 2018
View article titled, Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition
Open the PDF for Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition in another window
Includes: Supplementary data
Journal Articles

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma

Christian Grommes, Alessandro Pastore, Nicolaos Palaskas, Sarah S. Tang, Carl Campos, Derrek Schartz, Paolo Codega, Donna Nichol, Owen Clark, Wan-Ying Hsieh, Dan Rohle, Marc Rosenblum, Agnes Viale, Viviane S. Tabar, Cameron W. Brennan, Igor T. Gavrilovic, Thomas J. Kaley, Craig P. Nolan, Antonio Omuro, Elena Pentsova, Alissa A. Thomas, Elina Tsyvkin, Ariela Noy, M. Lia Palomba, Paul Hamlin, Craig S. Sauter, Craig H. Moskowitz, Julia Wolfe, Ahmet Dogan, Minhee Won, Jon Glass, Scott Peak, Enrico C. Lallana, Vaios Hatzoglou, Anne S. Reiner, Philip H. Gutin, Jason T. Huse, Katherine S. Panageas, Thomas G. Graeber, Nikolaus Schultz, Lisa M. DeAngelis, Ingo K. Mellinghoff
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (9): 1018–1029.
https://doi.org/10.1158/2159-8290.CD-17-0613
Published: 31 August 2017
View article titled, Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma
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Includes: Supplementary data
Journal Articles

Combined Inhibition of MAP Kinase and KIT Signaling Synergistically Destabilizes ETV1 and Suppresses GIST Tumor Growth

Leili Ran, Inna Sirota, Zhen Cao, Devan Murphy, Yuedan Chen, Shipra Shukla, Yuanyuan Xie, Michael C. Kaufmann, Dong Gao, Sinan Zhu, Ferdinando Rossi, John Wongvipat, Takahiro Taguchi, William D. Tap, Ingo K. Mellinghoff, Peter Besmer, Cristina R. Antonescu, Yu Chen, Ping Chi
Journal: Cancer Discovery
Cancer Discov (2015) 5 (3): 304–315.
https://doi.org/10.1158/2159-8290.CD-14-0985
Published: 05 March 2015
View article titled, Combined Inhibition of MAP Kinase and KIT Signaling Synergistically Destabilizes ETV1 and Suppresses GIST Tumor Growth
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Includes: Supplementary data
Journal Articles

Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors

Igor Vivanco, H. Ian Robins, Daniel Rohle, Carl Campos, Christian Grommes, Phioanh Leia Nghiemphu, Sara Kubek, Barbara Oldrini, Milan G. Chheda, Nicolas Yannuzzi, Hui Tao, Shaojun Zhu, Akio Iwanami, Daisuke Kuga, Julie Dang, Alicia Pedraza, Cameron W. Brennan, Adriana Heguy, Linda M. Liau, Frank Lieberman, W. K. Alfred Yung, Mark R. Gilbert, David A. Reardon, Jan Drappatz, Patrick Y. Wen, Kathleen R. Lamborn, Susan M. Chang, Michael D. Prados, Howard A. Fine, Steve Horvath, Nian Wu, Andrew B. Lassman, Lisa M. DeAngelis, William H. Yong, John G. Kuhn, Paul S. Mischel, Minesh P. Mehta, Timothy F. Cloughesy, Ingo K. Mellinghoff
Journal: Cancer Discovery
Cancer Discov (2012) 2 (5): 458–471.
https://doi.org/10.1158/2159-8290.CD-11-0284
Published: 09 May 2012
View article titled, Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors
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Includes: Multimedia, Supplementary data
Journal Articles

An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR–Dependent Pathway

Deliang Guo, Felicia Reinitz, Mary Youssef, Cynthia Hong, David Nathanson, David Akhavan, Daisuke Kuga, Ali Nael Amzajerdi, Horacio Soto, Shaojun Zhu, Ivan Babic, Kazuhiro Tanaka, Julie Dang, Akio Iwanami, Beatrice Gini, Jason DeJesus, Dominique D. Lisiero, Tiffany T. Huang, Robert M. Prins, Patrick Y. Wen, H. Ian Robins, Michael D. Prados, Lisa M. DeAngelis, Ingo K. Mellinghoff, Minesh P. Mehta, C. David James, Arnab Chakravarti, Timothy F. Cloughesy, Peter Tontonoz, Paul S. Mischel
Journal: Cancer Discovery
Cancer Discov (2011) 1 (5): 442–456.
https://doi.org/10.1158/2159-8290.CD-11-0102
Published: 18 October 2011
View article titled, An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR–Dependent Pathway
Open the PDF for An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR–Dependent Pathway in another window
Includes: Supplementary data