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Hyemin Lee
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Journal Articles

MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer

Jitendra K. Meena, Jarey H. Wang, Nicholas J. Neill, Dianne Keough, Nagireddy Putluri, Panagiotis Katsonis, Amanda M. Koire, Hyemin Lee, Elizabeth A. Bowling, Siddhartha Tyagi, Mayra Orellana, Rocio Dominguez-Vidaña, Heyuan Li, Kenneth Eagle, Charles Danan, Hsiang-Ching Chung, Andrew D. Yang, William Wu, Sarah J. Kurley, Brian M. Ho, Joseph R. Zoeller, Calla M. Olson, Kristen L. Meerbrey, Olivier Lichtarge, Arun Sreekumar, Clifford C. Dacso, Luke W. Guddat, Dominik Rejman, Dana Hocková, Zlatko Janeba, Lukas M. Simon, Charles Y. Lin, Monica C. Pillon, Thomas F. Westbrook
Journal: Cancer Discovery
Cancer Discov (2024) 14 (9): 1699–1716.
https://doi.org/10.1158/2159-8290.CD-22-0649
Published: 04 September 2024
View article titled, MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer
Open the PDF for MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers

Guang Lei, Chao Mao, Amber D. Horbath, Yuelong Yan, Shirong Cai, Jun Yao, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy A. Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
Journal: Cancer Discovery
Cancer Discov (2024) 14 (8): 1476–1495.
https://doi.org/10.1158/2159-8290.CD-23-1220
Published: 02 August 2024
View article titled, BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in <em>BRCA1</em>-Deficient Cancers
Open the PDF for BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in <em>BRCA1</em>-Deficient Cancers in another window
Includes: Supplementary data