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Gretchen M. Alicea
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Journal Articles

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Gretchen M. Alicea, Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera, Marie R. Webster, Curtis H. Kugel, III, Brett L. Ecker, M. Cecilia Caino, Andrew V. Kossenkov, Hsin-Yao Tang, Dennie T. Frederick, Keith T. Flaherty, Xiaowei Xu, Qin Liu, Dmitry I. Gabrilovich, Meenhard Herlyn, Ian A. Blair, Zachary T. Schug, David W. Speicher, Ashani T. Weeraratna
Journal: Cancer Discovery
Cancer Discov (2020) 10 (9): 1282–1295.
https://doi.org/10.1158/2159-8290.CD-20-0329
Published: 01 September 2020
View articletitled, Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2
Open the PDF for Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2 in another window
Includes: Multimedia, Supplementary data
Journal Articles

Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis

Yongkang Zou, Andrea Watters, Nan Cheng, Caroline E. Perry, Ke Xu, Gretchen M. Alicea, Joshua L.D. Parris, Ezra Baraban, Pulak Ray, Anupma Nayak, Xiaowei Xu, Meenhard Herlyn, Maureen E. Murphy, Ashani T. Weeraratna, Zachary T. Schug, Qing Chen
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (12): 1720–1735.
https://doi.org/10.1158/2159-8290.CD-19-0270
Published: 02 December 2019
View articletitled, Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis
Open the PDF for Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis in another window
Includes: Supplementary data
Journal Articles

PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer

Vito W. Rebecca, Michael C. Nicastri, Colin Fennelly, Cynthia I. Chude, Julie S. Barber-Rotenberg, Amruta Ronghe, Quentin McAfee, Noel P. McLaughlin, Gao Zhang, Aaron R. Goldman, Rani Ojha, Shengfu Piao, Estela Noguera-Ortega, Alessandra Martorella, Gretchen M. Alicea, Jennifer J. Lee, Lynn M. Schuchter, Xiaowei Xu, Meenhard Herlyn, Ronen Marmorstein, Phyllis A. Gimotty, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (2): 220–229.
https://doi.org/10.1158/2159-8290.CD-18-0706
Published: 08 February 2019
View articletitled, PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
Open the PDF for PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer in another window
Includes: Supplementary data
Journal Articles

Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis

Brett L. Ecker, Amanpreet Kaur, Stephen M. Douglass, Marie R. Webster, Filipe V. Almeida, Gloria E. Marino, Andrew J. Sinnamon, Madalyn G. Neuwirth, Gretchen M. Alicea, Abibatou Ndoye, Mitchell Fane, Xiaowei Xu, Myung Shin Sim, Gary B. Deutsch, Mark B. Faries, Giorgos C. Karakousis, Ashani T. Weeraratna
Journal: Cancer Discovery
Cancer Discov (2019) 9 (1): 82–95.
https://doi.org/10.1158/2159-8290.CD-18-0168
Published: 09 January 2019
View articletitled, Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis
Open the PDF for Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis in another window
Includes: Supplementary data
Journal Articles

A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles

Vito W. Rebecca, Michael C. Nicastri, Noel McLaughlin, Colin Fennelly, Quentin McAfee, Amruta Ronghe, Michel Nofal, Chun-Yan Lim, Eric Witze, Cynthia I. Chude, Gao Zhang, Gretchen M. Alicea, Shengfu Piao, Sengottuvelan Murugan, Rani Ojha, Samuel M. Levi, Zhi Wei, Julie S. Barber-Rotenberg, Maureen E. Murphy, Gordon B. Mills, Yiling Lu, Joshua Rabinowitz, Ronen Marmorstein, Qin Liu, Shujing Liu, Xiaowei Xu, Meenhard Herlyn, Roberto Zoncu, Donita C. Brady, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (11): 1266–1283.
https://doi.org/10.1158/2159-8290.CD-17-0741
Published: 01 November 2017
View articletitled, A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
Open the PDF for A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles in another window
Includes: Supplementary data