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Grant A. Challen
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Journal Articles

Enhanced Molecular Response in Myeloproliferative Neoplasms with Complete JAK2V617F Inhibition

Hamza Celik, Grant A. Challen
Journal: Cancer Discovery
Cancer Discov (2024) 14 (5): 701–703.
https://doi.org/10.1158/2159-8290.CD-23-1522
Published: 01 May 2024
View article titled, Enhanced Molecular Response in Myeloproliferative Neoplasms with Complete JAK2<sup>V617F</sup> Inhibition
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Journal Articles

Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis

Jennifer M. SanMiguel, Elizabeth Eudy, Matthew A. Loberg, Kira A. Young, Jayna J. Mistry, Kristina D. Mujica, Logan S. Schwartz, Timothy M. Stearns, Grant A. Challen, Jennifer J. Trowbridge
Journal: Cancer Discovery
Cancer Discov (2022) 12 (12): 2763–2773.
https://doi.org/10.1158/2159-8290.CD-22-0086
Published: 02 December 2022
View article titled, Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in <em>Dnmt3a</em>-Mutant Clonal Hematopoiesis
Open the PDF for Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in <em>Dnmt3a</em>-Mutant Clonal Hematopoiesis in another window
Includes: Supplementary data
Journal Articles

A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms

Hamza Celik, Ethan Krug, Christine R. Zhang, Wentao Han, Nancy Issa, Won Kyun Koh, Hassan Bjeije, Ostap Kukhar, Maggie Allen, Tiandao Li, Daniel A.C. Fisher, Jared S. Fowles, Terrence N. Wong, Matthew C. Stubbs, Holly K. Koblish, Stephen T. Oh, Grant A. Challen
Journal: Cancer Discovery
Cancer Discov (2021) 11 (12): 3126–3141.
https://doi.org/10.1158/2159-8290.CD-20-1652
Published: 02 December 2021
View article titled, A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
Open the PDF for A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms in another window
Includes: Supplementary data
Journal Articles

LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms

Christian Marinaccio, Praveen Suraneni, Hamza Celik, Andrew Volk, Qiang Jeremy Wen, Te Ling, Marinka Bulic, Terra Lasho, Richard P. Koche, Christopher A. Famulare, Noushin Farnoud, Brady Stein, Michael Schieber, Sandeep Gurbuxani, David E. Root, Scott T. Younger, Ronald Hoffman, Naseema Gangat, Panagiotis Ntziachristos, Navdeep S. Chandel, Ross L. Levine, Raajit K. Rampal, Grant A. Challen, Ayalew Tefferi, John D. Crispino
Journal: Cancer Discovery
Cancer Discov (2021) 11 (6): 1398–1410.
https://doi.org/10.1158/2159-8290.CD-20-1353
Published: 01 June 2021
View article titled, LKB1/<em>STK11</em> Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms
Open the PDF for LKB1/<em>STK11</em> Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms in another window
Includes: Supplementary data