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Giuseppe Rospo
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Journal Articles

Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Gabriele Picco, Chiara M. Cattaneo, Esmée J. van Vliet, Giovanni Crisafulli, Giuseppe Rospo, Sarah Consonni, Sara F. Vieira, Iñigo Sánchez Rodríguez, Carlotta Cancelliere, Ruby Banerjee, Luuk J. Schipper, Daniele Oddo, Krijn K. Dijkstra, Jindrich Cinatl, Martin Michaelis, Fengtang Yang, Federica Di Nicolantonio, Andrea Sartore-Bianchi, Salvatore Siena, Sabrina Arena, Emile E. Voest, Alberto Bardelli, Mathew J. Garnett
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (8): 1923–1937.
https://doi.org/10.1158/2159-8290.CD-20-1508
Published: 01 August 2021
View articletitled, Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy
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Includes: Supplementary data
Journal Articles

CD4 T Cell–Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair–Deficient Tumors

Giovanni Germano, Steve Lu, Giuseppe Rospo, Simona Lamba, Benoit Rousseau, Sonia Fanelli, Denise Stenech, Dung T. Le, John Hays, Maria Grazia Totaro, Vito Amodio, Rosaria Chilà, Anna Mondino, Luis A. Diaz, Jr., Federica Di Nicolantonio, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2021) 11 (7): 1844–1859.
https://doi.org/10.1158/2159-8290.CD-20-0987
Published: 01 July 2021
View articletitled, CD4 T Cell–Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair–Deficient Tumors
Open the PDF for CD4 T Cell–Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair–Deficient Tumors in another window
Includes: Supplementary data
Journal Articles

The Clinical Impact of the Genomic Landscape of Mismatch Repair–Deficient Cancers

Giovanni Germano, Nabil Amirouchene-Angelozzi, Giuseppe Rospo, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2018) 8 (12): 1518–1528.
https://doi.org/10.1158/2159-8290.CD-18-0150
Published: 03 December 2018
View articletitled, The Clinical Impact of the Genomic Landscape of Mismatch Repair–Deficient Cancers
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Journal Articles

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

Mariangela Russo, Sandra Misale, Ge Wei, Giulia Siravegna, Giovanni Crisafulli, Luca Lazzari, Giorgio Corti, Giuseppe Rospo, Luca Novara, Benedetta Mussolin, Alice Bartolini, Nicholas Cam, Roopal Patel, Shunqi Yan, Robert Shoemaker, Robert Wild, Federica Di Nicolantonio, Andrea Sartore Bianchi, Gang Li, Salvatore Siena, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2016) 6 (1): 36–44.
https://doi.org/10.1158/2159-8290.CD-15-0940
Published: 07 January 2016
View articletitled, Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer
Open the PDF for Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer in another window
Includes: Supplementary data