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Giovanni Crisafulli
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Journal Articles

Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients

Giovanni Crisafulli, Andrea Sartore-Bianchi, Luca Lazzari, Filippo Pietrantonio, Alessio Amatu, Marco Macagno, Ludovic Barault, Andrea Cassingena, Alice Bartolini, Paolo Luraghi, Gianluca Mauri, Paolo Battuello, Nicola Personeni, Maria Giulia Zampino, Valeria Pessei, Pietro Paolo Vitiello, Federica Tosi, Laura Idotta, Federica Morano, Emanuele Valtorta, Emanuela Bonoldi, Giovanni Germano, Federica Di Nicolantonio, Silvia Marsoni, Salvatore Siena, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2022) 12 (7): 1656–1675.
https://doi.org/10.1158/2159-8290.CD-21-1434
Published: 06 July 2022
View articletitled, Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients
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Includes: Supplementary data
Journal Articles

Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Gabriele Picco, Chiara M. Cattaneo, Esmée J. van Vliet, Giovanni Crisafulli, Giuseppe Rospo, Sarah Consonni, Sara F. Vieira, Iñigo Sánchez Rodríguez, Carlotta Cancelliere, Ruby Banerjee, Luuk J. Schipper, Daniele Oddo, Krijn K. Dijkstra, Jindrich Cinatl, Martin Michaelis, Fengtang Yang, Federica Di Nicolantonio, Andrea Sartore-Bianchi, Salvatore Siena, Sabrina Arena, Emile E. Voest, Alberto Bardelli, Mathew J. Garnett
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (8): 1923–1937.
https://doi.org/10.1158/2159-8290.CD-20-1508
Published: 01 August 2021
View articletitled, Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy
Open the PDF for Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer

Mariangela Russo, Giulia Siravegna, Lawrence S. Blaszkowsky, Giorgio Corti, Giovanni Crisafulli, Leanne G. Ahronian, Benedetta Mussolin, Eunice L. Kwak, Michela Buscarino, Luca Lazzari, Emanuele Valtorta, Mauro Truini, Nicholas A. Jessop, Hayley E. Robinson, Theodore S. Hong, Mari Mino-Kenudson, Federica Di Nicolantonio, Ashraf Thabet, Andrea Sartore-Bianchi, Salvatore Siena, A. John Iafrate, Alberto Bardelli, Ryan B. Corcoran
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (2): 147–153.
https://doi.org/10.1158/2159-8290.CD-15-1283
Published: 04 February 2016
View articletitled, Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer
Open the PDF for Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

Mariangela Russo, Sandra Misale, Ge Wei, Giulia Siravegna, Giovanni Crisafulli, Luca Lazzari, Giorgio Corti, Giuseppe Rospo, Luca Novara, Benedetta Mussolin, Alice Bartolini, Nicholas Cam, Roopal Patel, Shunqi Yan, Robert Shoemaker, Robert Wild, Federica Di Nicolantonio, Andrea Sartore Bianchi, Gang Li, Salvatore Siena, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2016) 6 (1): 36–44.
https://doi.org/10.1158/2159-8290.CD-15-0940
Published: 07 January 2016
View articletitled, Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer
Open the PDF for Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer in another window
Includes: Supplementary data