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Franck Housseau
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Journal Articles

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

Julia L. Drewes, Jie Chen, Nicholas O. Markham, Reece J. Knippel, Jada C. Domingue, Ada J. Tam, June L. Chan, Lana Kim, Madison McMann, Courtney Stevens, Christine M. Dejea, Sarah Tomkovich, John Michel, James R. White, Fuad Mohammad, Victoria L. Campodónico, Cody N. Heiser, Xinqun Wu, Shaoguang Wu, Hua Ding, Patricia Simner, Karen Carroll, Martha J. Shrubsole, Robert A. Anders, Seth T. Walk, Christian Jobin, Fengyi Wan, Robert J. Coffey, Franck Housseau, Ken S. Lau, Cynthia L. Sears
Journal: Cancer Discovery
Cancer Discov (2022) 12 (8): 1873–1885.
https://doi.org/10.1158/2159-8290.CD-21-1273
Published: 05 August 2022
View articletitled, Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
Open the PDF for Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice in another window
Includes: Supplementary data
Journal Articles

Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy

Christina E. DeStefano Shields, James R. White, Liam Chung, Alyssa Wenzel, Jessica L. Hicks, Ada J. Tam, June L. Chan, Christine M. Dejea, Hongni Fan, John Michel, Ashley R. Maiuri, Shruthi Sriramkumar, Ram Podicheti, Douglas B. Rusch, Hao Wang, Angelo M. De Marzo, Sepideh Besharati, Robert A. Anders, Stephen B. Baylin, Heather M. O'Hagan, Franck Housseau, Cynthia L. Sears
Journal: Cancer Discovery
Cancer Discov (2021) 11 (7): 1792–1807.
https://doi.org/10.1158/2159-8290.CD-20-0770
Published: 01 July 2021
View articletitled, Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy
Open the PDF for Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy in another window
Includes: Supplementary data
Journal Articles

Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis

Abby L. Geis, Hongni Fan, Xinqun Wu, Shaoguang Wu, David L. Huso, Jaime L. Wolfe, Cynthia L. Sears, Drew M. Pardoll, Franck Housseau
Journal: Cancer Discovery
Cancer Discov (2015) 5 (10): 1098–1109.
https://doi.org/10.1158/2159-8290.CD-15-0447
Published: 30 September 2015
View articletitled, Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
Open the PDF for Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis in another window
Includes: Supplementary data
Journal Articles

The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints

Nicolas J. Llosa, Michael Cruise, Ada Tam, Elizabeth C. Wicks, Elizabeth M. Hechenbleikner, Janis M. Taube, Richard L. Blosser, Hongni Fan, Hao Wang, Brandon S. Luber, Ming Zhang, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Cynthia L. Sears, Robert A. Anders, Drew M. Pardoll, Franck Housseau
Journal: Cancer Discovery
Cancer Discov (2015) 5 (1): 43–51.
https://doi.org/10.1158/2159-8290.CD-14-0863
Published: 11 January 2015
View articletitled, The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Open the PDF for The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints in another window
Includes: Supplementary data