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Francisco J. Sánchez-Rivera
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Journal Articles

A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition

Yadira M. Soto-Feliciano, Francisco J. Sánchez-Rivera, Florian Perner, Douglas W. Barrows, Edward R. Kastenhuber, Yu-Jui Ho, Thomas Carroll, Yijun Xiong, Disha Anand, Alexey A. Soshnev, Leah Gates, Mary Clare Beytagh, David Cheon, Shengqing Gu, X. Shirley Liu, Andrei V. Krivtsov, Maximiliano Meneses, Elisa de Stanchina, Richard M. Stone, Scott A. Armstrong, Scott W. Lowe, C. David Allis
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 146–169.
https://doi.org/10.1158/2159-8290.CD-22-0416
Published: 09 January 2023
View article titled, A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition
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Includes: Supplementary data
Journal Articles

Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

Carla P. Concepcion, Sai Ma, Lindsay M. LaFave, Arjun Bhutkar, Manyuan Liu, Lydia P. DeAngelo, Jonathan Y. Kim, Isabella Del Priore, Adam J. Schoenfeld, Manon Miller, Vinay K. Kartha, Peter M.K. Westcott, Francisco J. Sánchez-Rivera, Kevin Meli, Manav Gupta, Roderick T. Bronson, Gregory J. Riely, Natasha Rekhtman, Charles M. Rudin, Carla F. Kim, Aviv Regev, Jason D. Buenrostro, Tyler Jacks
Journal: Cancer Discovery
Cancer Discov (2022) 12 (2): 562–585.
https://doi.org/10.1158/2159-8290.CD-21-0248
Published: 09 February 2022
View article titled, <em>Smarca4</em> Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung
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Includes: Supplementary data
Journal Articles

Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

Metamia Ciampricotti, Triantafyllia Karakousi, Allison L. Richards, Àlvaro Quintanal-Villalonga, Angeliki Karatza, Rebecca Caeser, Emily A. Costa, Viola Allaj, Parvathy Manoj, Kyle B. Spainhower, Faruk E. Kombak, Francisco J. Sanchez-Rivera, Janneke E. Jaspers, Anastasia-Maria Zavitsanou, Danilo Maddalo, Andrea Ventura, William M. Rideout, III, Elliot H. Akama-Garren, Tyler Jacks, Mark T.A. Donoghue, Triparna Sen, Trudy G. Oliver, John T. Poirier, Thales Papagiannakopoulos, Charles M. Rudin
Journal: Cancer Discovery
Cancer Discov (2021) 11 (12): 3214–3229.
https://doi.org/10.1158/2159-8290.CD-21-0441
Published: 02 December 2021
View article titled, <em>Rlf–Mycl</em> Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer
Open the PDF for <em>Rlf–Mycl</em> Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis

Josef Leibold, Marcus Ruscetti, Zhen Cao, Yu-Jui Ho, Timour Baslan, Min Zou, Wassim Abida, Judith Feucht, Teng Han, Francisco M. Barriga, Kaloyan M. Tsanov, Leah Zamechek, Amanda Kulick, Corina Amor, Sha Tian, Katarzyna Rybczyk, Nelson R. Salgado, Francisco J. Sánchez-Rivera, Philip A. Watson, Elisa de Stanchina, John E. Wilkinson, Lukas E. Dow, Cory Abate-Shen, Charles L. Sawyers, Scott W. Lowe
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (7): 1038–1057.
https://doi.org/10.1158/2159-8290.CD-19-1242
Published: 01 July 2020
View article titled, Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis
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Includes: Supplementary data
Journal Articles

Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression

Salina Yuan, Ramakrishnan Natesan, Francisco J. Sanchez-Rivera, Jinyang Li, Natarajan V. Bhanu, Taiji Yamazoe, Jeffrey H. Lin, Allyson J. Merrell, Yogev Sela, Stacy K. Thomas, Yanqing Jiang, Jacqueline B. Plesset, Emma M. Miller, Junwei Shi, Benjamin A. Garcia, Scott W. Lowe, Irfan A. Asangani, Ben Z. Stanger
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (6): 854–871.
https://doi.org/10.1158/2159-8290.CD-19-1299
Published: 01 June 2020
View article titled, Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression
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Includes: Supplementary data
Journal Articles

A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1

Evangelia Loizou, Ana Banito, Geulah Livshits, Yu-Jui Ho, Richard P. Koche, Francisco J. Sánchez-Rivera, Allison Mayle, Chi-Chao Chen, Savvas Kinalis, Frederik O. Bagger, Edward R. Kastenhuber, Benjamin H. Durham, Scott W. Lowe
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (7): 962–979.
https://doi.org/10.1158/2159-8290.CD-18-1391
Published: 01 July 2019
View article titled, A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1
Open the PDF for A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1 in another window
Includes: Supplementary data