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Filip Janku
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Journal Articles

Advances on the BRAF Front in Colorectal Cancer

Filip Janku
Journal: Cancer Discovery
Cancer Discov (2018) 8 (4): 389–391.
https://doi.org/10.1158/2159-8290.CD-18-0125
Published: 01 April 2018
View article titled, Advances on the BRAF Front in Colorectal Cancer
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Journal Articles

First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study

Ryan J. Sullivan, Jeffrey R. Infante, Filip Janku, Deborah Jean Lee Wong, Jeffrey A. Sosman, Vicki Keedy, Manish R. Patel, Geoffrey I. Shapiro, James W. Mier, Anthony W. Tolcher, Andrea Wang-Gillam, Mario Sznol, Keith Flaherty, Elizabeth Buchbinder, Richard D. Carvajal, Anna M. Varghese, Mario E. Lacouture, Antoni Ribas, Sapna P. Patel, Gary A. DeCrescenzo, Caroline M. Emery, Anna L. Groover, Saurabh Saha, Mary Varterasian, Dean J. Welsch, David M. Hyman, Bob T. Li
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (2): 184–195.
https://doi.org/10.1158/2159-8290.CD-17-1119
Published: 04 February 2018
View article titled, First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study
Open the PDF for First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study in another window
Includes: Supplementary data
Journal Articles

Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation

David S. Hong, Van K. Morris, Badi El Osta, Alexey V. Sorokin, Filip Janku, Siqing Fu, Michael J. Overman, Sarina Piha-Paul, Vivek Subbiah, Bryan Kee, Apostolia M. Tsimberidou, David Fogelman, Jorge Bellido, Imad Shureiqi, Helen Huang, Johnique Atkins, Gabi Tarcic, Nicolas Sommer, Richard Lanman, Funda Meric-Bernstam, Scott Kopetz
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (12): 1352–1365.
https://doi.org/10.1158/2159-8290.CD-16-0050
Published: 04 December 2016
View article titled, Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with <em>BRAF</em><sup>V600E</sup> Mutation
Open the PDF for Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with <em>BRAF</em><sup>V600E</sup> Mutation in another window
Includes: Supplementary data
Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Eli L. Diamond, Benjamin H. Durham, Julien Haroche, Zhan Yao, Jing Ma, Sameer A. Parikh, Zhaoming Wang, John Choi, Eunhee Kim, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, Patrick Campbell, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Olga Aminova, Adriana Heguy, Paul Zappile, Joy Nakitandwe, Chezi Ganzel, James D. Dalton, David W. Ellison, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, Philip J. Stephens, Vincent A. Miller, Jeffrey S. Ross, Siraj M. Ali, Samuel R. Briggs, Omotayo Fasan, Jared Block, Sebastien Héritier, Jean Donadieu, David B. Solit, David M. Hyman, José Baselga, Filip Janku, Barry S. Taylor, Christopher Y. Park, Zahir Amoura, Ahmet Dogan, Jean-Francois Emile, Neal Rosen, Tanja A. Gruber, Omar Abdel-Wahab
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (2): 154–165.
https://doi.org/10.1158/2159-8290.CD-15-0913
Published: 04 February 2016
View article titled, Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms
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Includes: Supplementary data
Journal Articles

Prospective Blinded Study of BRAFV600E Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders

David M. Hyman, Eli L. Diamond, Cecile Rose T. Vibat, Latifa Hassaine, Jason C. Poole, Minal Patel, Veronica R. Holley, Goran Cabrilo, Timothy T. Lu, Maria E. Arcila, Young Rock Chung, Raajit Rampal, Mario E. Lacouture, Neal Rosen, Funda Meric-Bernstam, José Baselga, Razelle Kurzrock, Mark G. Erlander, Filip Janku, Omar Abdel-Wahab
Journal: Cancer Discovery
Cancer Discov (2015) 5 (1): 64–71.
https://doi.org/10.1158/2159-8290.CD-14-0742
Published: 11 January 2015
View article titled, Prospective Blinded Study of <em>BRAF</em><sup>V600E</sup> Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders
Open the PDF for Prospective Blinded Study of <em>BRAF</em><sup>V600E</sup> Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders in another window
Includes: Supplementary data