1-5 of 5
David W. Speicher
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition

Vaibhav Jain, Sandra L. Harper, Amanda M. Versace, Dylan Fingerman, Gregory Schuyler Brown, Monika Bhardwaj, Mary Ann S. Crissey, Aaron R. Goldman, Gordon Ruthel, Qin Liu, Aleksandra Zivkovic, Holgar Stark, Meenhard Herlyn, Phyllis A. Gimotty, David W. Speicher, Ravi K. Amaravadi
Journal: Cancer Discovery
Cancer Discov (2023) 13 (2): 454–473.
https://doi.org/10.1158/2159-8290.CD-22-0535
Published: 06 February 2023
View articletitled, Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
Open the PDF for Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition in another window
Includes: Supplementary data
Journal Articles

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Gretchen M. Alicea, Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera, Marie R. Webster, Curtis H. Kugel, III, Brett L. Ecker, M. Cecilia Caino, Andrew V. Kossenkov, Hsin-Yao Tang, Dennie T. Frederick, Keith T. Flaherty, Xiaowei Xu, Qin Liu, Dmitry I. Gabrilovich, Meenhard Herlyn, Ian A. Blair, Zachary T. Schug, David W. Speicher, Ashani T. Weeraratna
Journal: Cancer Discovery
Cancer Discov (2020) 10 (9): 1282–1295.
https://doi.org/10.1158/2159-8290.CD-20-0329
Published: 01 September 2020
View articletitled, Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2
Open the PDF for Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2 in another window
Includes: Multimedia, Supplementary data
Journal Articles

PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer

Vito W. Rebecca, Michael C. Nicastri, Colin Fennelly, Cynthia I. Chude, Julie S. Barber-Rotenberg, Amruta Ronghe, Quentin McAfee, Noel P. McLaughlin, Gao Zhang, Aaron R. Goldman, Rani Ojha, Shengfu Piao, Estela Noguera-Ortega, Alessandra Martorella, Gretchen M. Alicea, Jennifer J. Lee, Lynn M. Schuchter, Xiaowei Xu, Meenhard Herlyn, Ronen Marmorstein, Phyllis A. Gimotty, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (2): 220–229.
https://doi.org/10.1158/2159-8290.CD-18-0706
Published: 08 February 2019
View articletitled, PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
Open the PDF for PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer in another window
Includes: Supplementary data
Journal Articles

Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility

Amanpreet Kaur, Brett L. Ecker, Stephen M. Douglass, Curtis H. Kugel, III, Marie R. Webster, Filipe V. Almeida, Rajasekharan Somasundaram, James Hayden, Ehsan Ban, Hossein Ahmadzadeh, Janusz Franco-Barraza, Neelima Shah, Ian A. Mellis, Frederick Keeney, Andrew Kossenkov, Hsin-Yao Tang, Xiangfan Yin, Qin Liu, Xiaowei Xu, Mitchell Fane, Patricia Brafford, Meenhard Herlyn, David W. Speicher, Jennifer A. Wargo, Michael T. Tetzlaff, Lauren E. Haydu, Arjun Raj, Vivek Shenoy, Edna Cukierman, Ashani T. Weeraratna
Journal: Cancer Discovery
Cancer Discov (2019) 9 (1): 64–81.
https://doi.org/10.1158/2159-8290.CD-18-0193
Published: 09 January 2019
View articletitled, Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility
Open the PDF for Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility in another window
Includes: Multimedia, Supplementary data
Journal Articles

A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles

Vito W. Rebecca, Michael C. Nicastri, Noel McLaughlin, Colin Fennelly, Quentin McAfee, Amruta Ronghe, Michel Nofal, Chun-Yan Lim, Eric Witze, Cynthia I. Chude, Gao Zhang, Gretchen M. Alicea, Shengfu Piao, Sengottuvelan Murugan, Rani Ojha, Samuel M. Levi, Zhi Wei, Julie S. Barber-Rotenberg, Maureen E. Murphy, Gordon B. Mills, Yiling Lu, Joshua Rabinowitz, Ronen Marmorstein, Qin Liu, Shujing Liu, Xiaowei Xu, Meenhard Herlyn, Roberto Zoncu, Donita C. Brady, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (11): 1266–1283.
https://doi.org/10.1158/2159-8290.CD-17-0741
Published: 01 November 2017
View articletitled, A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
Open the PDF for A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles in another window
Includes: Supplementary data