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David M. Sabatini
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Journal Articles

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

Bryan Ngo, Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J. Liang, Alba Luengo, Shawn M. Davidson, Ahmed Ali, Gino B. Ferraro, Grant M. Fischer, Roozbeh Eskandari, Diane S. Kang, Jing Ni, Ariana Plasger, Vinagolu K. Rajasekhar, Edward R. Kastenhuber, Sarah Bacha, Roshan K. Sriram, Benjamin D. Stein, Samuel F. Bakhoum, Matija Snuderl, Paolo Cotzia, John H. Healey, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, David M. Sabatini, Drew R. Jones, Min Yu, Jean J. Zhao, Rakesh K. Jain, Kayvan R. Keshari, Michael A. Davies, Matthew G. Vander Heiden, Eva Hernando, Matthias Mann, Lewis C. Cantley, Michael E. Pacold
Journal: Cancer Discovery
Cancer Discov (2020) 10 (9): 1352–1373.
https://doi.org/10.1158/2159-8290.CD-19-1228
Published: 01 September 2020
View article titled, Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
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Includes: Supplementary data
Journal Articles

Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib

Nikhil Wagle, Brian C. Grabiner, Eliezer M. Van Allen, Eran Hodis, Susanna Jacobus, Jeffrey G. Supko, Michelle Stewart, Toni K. Choueiri, Leena Gandhi, James M. Cleary, Aymen A. Elfiky, Mary Ellen Taplin, Edward C. Stack, Sabina Signoretti, Massimo Loda, Geoffrey I. Shapiro, David M. Sabatini, Eric S. Lander, Stacey B. Gabriel, Philip W. Kantoff, Levi A. Garraway, Jonathan E. Rosenberg
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (5): 546–553.
https://doi.org/10.1158/2159-8290.CD-13-0353
Published: 01 May 2014
View article titled, Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib
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Includes: Supplementary data
Journal Articles

A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

Brian C. Grabiner, Valentina Nardi, Kıvanç Birsoy, Richard Possemato, Kuang Shen, Sumi Sinha, Alexander Jordan, Andrew H. Beck, David M. Sabatini
Journal: Cancer Discovery
Cancer Discov (2014) 4 (5): 554–563.
https://doi.org/10.1158/2159-8290.CD-13-0929
Published: 01 May 2014
View article titled, A Diverse Array of Cancer-Associated <em>MTOR</em> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity
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Includes: Supplementary data
Journal Articles

Pten-Null Tumors Cohabiting the Same Lung Display Differential AKT Activation and Sensitivity to Dietary Restriction

Natasha L. Curry, Mari Mino-Kenudson, Trudy G. Oliver, Ömer H. Yilmaz, Vedat O. Yilmaz, Jade Y. Moon, Tyler Jacks, David M. Sabatini, Nada Y. Kalaany
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (8): 908–921.
https://doi.org/10.1158/2159-8290.CD-12-0507
Published: 07 August 2013
View article titled, <em>Pten</em>-Null Tumors Cohabiting the Same Lung Display Differential AKT Activation and Sensitivity to Dietary Restriction
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Includes: Supplementary data
Journal Articles

Cancer Cell Metabolism: One Hallmark, Many Faces

Jason R. Cantor, David M. Sabatini
Journal: Cancer Discovery
Cancer Discov (2012) 2 (10): 881–898.
https://doi.org/10.1158/2159-8290.CD-12-0345
Published: 14 October 2012
View article titled, Cancer Cell Metabolism: One Hallmark, Many Faces
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