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David M. Barrett
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Journal Articles

Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy

Gregory M. Chen, Changya Chen, Rajat K. Das, Peng Gao, Chia-Hui Chen, Shovik Bandyopadhyay, Yang-Yang Ding, Yasin Uzun, Wenbao Yu, Qin Zhu, Regina M. Myers, Stephan A. Grupp, David M. Barrett, Kai Tan
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (9): 2186–2199.
https://doi.org/10.1158/2159-8290.CD-20-1677
Published: 01 September 2021
View articletitled, Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy
Open the PDF for Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy in another window
Includes: Supplementary data
Journal Articles

Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers

Rajat K. Das, Lauren Vernau, Stephan A. Grupp, David M. Barrett
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (4): 492–499.
https://doi.org/10.1158/2159-8290.CD-18-1314
Published: 01 April 2019
View articletitled, Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers
Open the PDF for Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers in another window
Includes: Supplementary data
Journal Articles

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

David T. Teachey, Simon F. Lacey, Pamela A. Shaw, J. Joseph Melenhorst, Shannon L. Maude, Noelle Frey, Edward Pequignot, Vanessa E. Gonzalez, Fang Chen, Jeffrey Finklestein, David M. Barrett, Scott L. Weiss, Julie C. Fitzgerald, Robert A. Berg, Richard Aplenc, Colleen Callahan, Susan R. Rheingold, Zhaohui Zheng, Stefan Rose-John, Jason C. White, Farzana Nazimuddin, Gerald Wertheim, Bruce L. Levine, Carl H. June, David L. Porter, Stephan A. Grupp
Journal: Cancer Discovery
Cancer Discov (2016) 6 (6): 664–679.
https://doi.org/10.1158/2159-8290.CD-16-0040
Published: 02 June 2016
View articletitled, Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia
Open the PDF for Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

Elena Sotillo, David M. Barrett, Kathryn L. Black, Asen Bagashev, Derek Oldridge, Glendon Wu, Robyn Sussman, Claudia Lanauze, Marco Ruella, Matthew R. Gazzara, Nicole M. Martinez, Colleen T. Harrington, Elaine Y. Chung, Jessica Perazzelli, Ted J. Hofmann, Shannon L. Maude, Pichai Raman, Alejandro Barrera, Saar Gill, Simon F. Lacey, Jan J. Melenhorst, David Allman, Elad Jacoby, Terry Fry, Crystal Mackall, Yoseph Barash, Kristen W. Lynch, John M. Maris, Stephan A. Grupp, Andrei Thomas-Tikhonenko
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (12): 1282–1295.
https://doi.org/10.1158/2159-8290.CD-15-1020
Published: 03 December 2015
View articletitled, Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
Open the PDF for Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy in another window
Includes: Supplementary data