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David Cunningham
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Journal Articles

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Free
Khurum H. Khan, David Cunningham, Benjamin Werner, Georgios Vlachogiannis, Inmaculada Spiteri, Timon Heide, Javier Fernandez Mateos, Alexandra Vatsiou, Andrea Lampis, Mahnaz Darvish Damavandi, Hazel Lote, Ian Said Huntingford, Somaieh Hedayat, Ian Chau, Nina Tunariu, Giulia Mentrasti, Francesco Trevisani, Sheela Rao, Gayathri Anandappa, David Watkins, Naureen Starling, Janet Thomas, Clare Peckitt, Nasir Khan, Massimo Rugge, Ruwaida Begum, Blanka Hezelova, Annette Bryant, Thomas Jones, Paula Proszek, Matteo Fassan, Jens C. Hahne, Michael Hubank, Chiara Braconi, Andrea Sottoriva, Nicola Valeri
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (10): 1270–1285.
https://doi.org/10.1158/2159-8290.CD-17-0891
Published: 02 October 2018
View articletitled, Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial
Open the PDF for Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial in another window
Includes: Supplementary data
Journal Articles

High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Free
Alex Pearson, Elizabeth Smyth, Irina S. Babina, Maria Teresa Herrera-Abreu, Noelia Tarazona, Clare Peckitt, Elaine Kilgour, Neil R. Smith, Catherine Geh, Claire Rooney, Ros Cutts, James Campbell, Jian Ning, Kerry Fenwick, Amanda Swain, Gina Brown, Sue Chua, Anne Thomas, Stephen R.D. Johnston, Mazhar Ajaz, Katherine Sumpter, Angela Gillbanks, David Watkins, Ian Chau, Sanjay Popat, David Cunningham, Nicholas C. Turner
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (8): 838–851.
https://doi.org/10.1158/2159-8290.CD-15-1246
Published: 01 August 2016
View articletitled, High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial
Open the PDF for High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial in another window
Includes: Supplementary data
Journal Articles

Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation

Available to Purchase
Anna Sukhanova, Andrey Gorin, Ilya G. Serebriiskii, Linara Gabitova, Hui Zheng, Diana Restifo, Brian L. Egleston, David Cunningham, Tetyana Bagnyukova, Hanqing Liu, Anna Nikonova, Gregory P. Adams, Yan Zhou, Dong-Hua Yang, Ranee Mehra, Barbara Burtness, Kathy Q. Cai, Andres Klein-Szanto, Lisa E. Kratz, Richard I. Kelley, Louis M. Weiner, Gail E. Herman, Erica A. Golemis, Igor Astsaturov
Journal: Cancer Discovery
Cancer Discov (2013) 3 (1): 96–111.
https://doi.org/10.1158/2159-8290.CD-12-0031
Published: 13 January 2013
View articletitled, Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation
Open the PDF for Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation in another window
Includes: Supplementary data