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Chunxiao Xu
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Journal Articles

Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer

Erin M. Tricker, Chunxiao Xu, Sharmeen Uddin, Marzia Capelletti, Dalia Ercan, Atsuko Ogino, Christine A. Pratilas, Neal Rosen, Nathanael S. Gray, Kwok-Kin Wong, Pasi A. Jänne
Journal: Cancer Discovery
Cancer Discov (2015) 5 (9): 960–971.
https://doi.org/10.1158/2159-8290.CD-15-0063
Published: 01 September 2015
View article titled, Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in <em>EGFR</em>-Mutant Lung Cancer
Open the PDF for Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in <em>EGFR</em>-Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

Yan Liu, Kevin Marks, Glenn S. Cowley, Julian Carretero, Qingsong Liu, Thomas J.F. Nieland, Chunxiao Xu, Travis J. Cohoon, Peng Gao, Yong Zhang, Zhao Chen, Abigail B. Altabef, Jeremy H. Tchaicha, Xiaoxu Wang, Sung Choe, Edward M. Driggers, Jianming Zhang, Sean T. Bailey, Norman E. Sharpless, D. Neil Hayes, Nirali M. Patel, Pasi A. Janne, Nabeel Bardeesy, Jeffrey A. Engelman, Brendan D. Manning, Reuben J. Shaw, John M. Asara, Ralph Scully, Alec Kimmelman, Lauren A. Byers, Don L. Gibbons, Ignacio I. Wistuba, John V. Heymach, David J. Kwiatkowski, William Y. Kim, Andrew L. Kung, Nathanael S. Gray, David E. Root, Lewis C. Cantley, Kwok-Kin Wong
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (8): 870–879.
https://doi.org/10.1158/2159-8290.CD-13-0015
Published: 07 August 2013
View article titled, Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in <em>LKB1</em>-Mutant Lung Cancer
Open the PDF for Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in <em>LKB1</em>-Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

Dalia Ercan, Chunxiao Xu, Masahiko Yanagita, Calixte S. Monast, Christine A. Pratilas, Joan Montero, Mohit Butaney, Takeshi Shimamura, Lynette Sholl, Elena V. Ivanova, Madhavi Tadi, Andrew Rogers, Claire Repellin, Marzia Capelletti, Ophélia Maertens, Eva M. Goetz, Anthony Letai, Levi A. Garraway, Matthew J. Lazzara, Neal Rosen, Nathanael S. Gray, Kwok-Kin Wong, Pasi A. Jänne
Journal: Cancer Discovery
Cancer Discov (2012) 2 (10): 934–947.
https://doi.org/10.1158/2159-8290.CD-12-0103
Published: 14 October 2012
View article titled, Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors
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Includes: Supplementary data
Journal Articles

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

Peter S. Hammerman, Martin L. Sos, Alex H. Ramos, Chunxiao Xu, Amit Dutt, Wenjun Zhou, Lear E. Brace, Brittany A. Woods, Wenchu Lin, Jianming Zhang, Xianming Deng, Sang Min Lim, Stefanie Heynck, Martin Peifer, Jeffrey R. Simard, Michael S. Lawrence, Robert C. Onofrio, Helga B. Salvesen, Danila Seidel, Thomas Zander, Johannes M. Heuckmann, Alex Soltermann, Holger Moch, Mirjam Koker, Frauke Leenders, Franziska Gabler, Silvia Querings, Sascha Ansén, Elisabeth Brambilla, Christian Brambilla, Philippe Lorimier, Odd Terje Brustugun, Åslaug Helland, Iver Petersen, Joachim H. Clement, Harry Groen, Wim Timens, Hannie Sietsma, Erich Stoelben, Jürgen Wolf, David G. Beer, Ming Sound Tsao, Megan Hanna, Charles Hatton, Michael J. Eck, Pasi A. Janne, Bruce E. Johnson, Wendy Winckler, Heidi Greulich, Adam J. Bass, Jeonghee Cho, Daniel Rauh, Nathanael S. Gray, Kwok-Kin Wong, Eric B. Haura, Roman K. Thomas, Matthew Meyerson
Journal: Cancer Discovery
Cancer Discov (2011) 1 (1): 78–89.
https://doi.org/10.1158/2159-8274.CD-11-0005
Published: 01 June 2011
View article titled, Mutations in the <em>DDR2</em> Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
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Includes: Multimedia, Supplementary data