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Charlie Hatton
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Journal Articles

KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia

Open Access
Nicole L. Michmerhuizen, Emily B. Heikamp, Ilaria Iacobucci, Masayuki Umeda, Bright Arthur, Vibhor Mishra, Chun Shik Park, Danika Di Giacomo, Ryan Hiltenbrand, Qingsong Gao, Sandi Radko-Juettner, Josi Lott, Cynthia Martucci, Varsha Subramanyam, Charlie Hatton, Daniela V. Wenge, Pradyuamna Baviskar, Pablo Portola, Aurelie Claquin, Bappaditya Chandra, David W. Baggett, Ali Khalighifar, Hongling Huang, Peipei Zhou, Lingyun Long, Hao Shi, Yu Sun, Evangelia K. Papachristou, Chandra Sekhar Reddy Chilamakuri, Francisca N. de Luna Vitorino, Joanna M. Gongora, Huiyun Wu, Stanley B. Pounds, Laura J. Janke, Alex Kentsis, Clive S. D'Santos, Benjamin A. Garcia, Richard W. Kriwacki, Hongbo Chi, Jeffery M. Klco, Scott A. Armstrong, Charles G. Mullighan
Journal: Cancer Discovery
Cancer Discov (2025)
https://doi.org/10.1158/2159-8290.CD-24-1772
Published: 19 June 2025
View articletitled, KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia
Open the PDF for KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

Available to Purchase
Hannah J. Uckelmann, Elena L. Haarer, Reina Takeda, Eric M. Wong, Charlie Hatton, Christian Marinaccio, Florian Perner, Masooma Rajput, Noa J.C. Antonissen, Yanhe Wen, Lu Yang, Lorenzo Brunetti, Chun-Wei Chen, Scott A. Armstrong
Journal: Cancer Discovery
Cancer Discov (2023) 13 (3): 746–765.
https://doi.org/10.1158/2159-8290.CD-22-0366
Published: 01 March 2023
View articletitled, Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia
Open the PDF for Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

MOZ and Menin–MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor

Available to Purchase
Matthew L. Hemming, Morgan R. Benson, Michael A. Loycano, Justin A. Anderson, Jessica L. Andersen, Madeleine L. Taddei, Andrei V. Krivtsov, Brandon J. Aubrey, Jevon A. Cutler, Charlie Hatton, Ewa Sicinska, Scott A. Armstrong
Journal: Cancer Discovery
Cancer Discov (2022) 12 (7): 1804–1823.
https://doi.org/10.1158/2159-8290.CD-21-0646
Published: 06 July 2022
View articletitled, MOZ and Menin–MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
Open the PDF for MOZ and Menin–MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor in another window
Includes: Supplementary data