1-9 of 9
Cem Meydan
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas

Leandro Venturutti, Martin A. Rivas, Benedikt W. Pelzer, Ruth Flümann, Julia Hansen, Ioannis Karagiannidis, Min Xia, Dylan R. McNally, Yusuke Isshiki, Andrew Lytle, Matt Teater, Christopher R. Chin, Cem Meydan, Gero Knittel, Edd Ricker, Christopher E. Mason, Xiaofei Ye, Qiang Pan-Hammarström, Christian Steidl, David W. Scott, Hans Christian Reinhardt, Alessandra B. Pernis, Wendy Béguelin, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 216–243.
https://doi.org/10.1158/2159-8290.CD-22-0561
Published: 09 January 2023
View articletitled, An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
Open the PDF for An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas in another window
Includes: Supplementary data
Journal Articles

BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL

Min Xia, Liron David, Matt Teater, Johana Gutierrez, Xiang Wang, Cem Meydan, Andrew Lytle, Graham W. Slack, David W. Scott, Ryan D. Morin, Ozlem Onder, Kojo S.J. Elenitoba-Johnson, Nahuel Zamponi, Leandro Cerchietti, Tianbao Lu, Ulrike Philippar, Lorena Fontan, Hao Wu, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2022) 12 (8): 1922–1941.
https://doi.org/10.1158/2159-8290.CD-21-1566
Published: 05 August 2022
View articletitled, BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL
Open the PDF for BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL in another window
Includes: Multimedia, Supplementary data
Journal Articles

SETD2 Haploinsufficiency Enhances Germinal Center–Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis

Wilfred Leung, Matt Teater, Ceyda Durmaz, Cem Meydan, Alexandra G. Chivu, Amy Chadburn, Edward J. Rice, Ashlesha Muley, Jeannie M. Camarillo, Jaison Arivalagan, Ziyi Li, Christopher R. Flowers, Neil L. Kelleher, Charles G. Danko, Marcin Imielinski, Sandeep S. Dave, Scott A. Armstrong, Christopher E. Mason, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2022) 12 (7): 1782–1803.
https://doi.org/10.1158/2159-8290.CD-21-1514
Published: 06 July 2022
View articletitled, SETD2 Haploinsufficiency Enhances Germinal Center–Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis
Open the PDF for SETD2 Haploinsufficiency Enhances Germinal Center–Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis in another window
Includes: Supplementary data
Journal Articles

Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence

Cihangir Duy, Meng Li, Matt Teater, Cem Meydan, Francine E. Garrett-Bakelman, Tak C. Lee, Christopher R. Chin, Ceyda Durmaz, Kimihito C. Kawabata, Eugen Dhimolea, Constantine S. Mitsiades, Hartmut Doehner, Richard J. D'Andrea, Michael W. Becker, Elisabeth M. Paietta, Christopher E. Mason, Martin Carroll, Ari M. Melnick
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (6): 1542–1561.
https://doi.org/10.1158/2159-8290.CD-20-1375
Published: 01 June 2021
View articletitled, Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence
Open the PDF for Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence in another window
Includes: Supplementary data
Journal Articles

Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML

Sheng Li, Xiaowen Chen, Jiahui Wang, Cem Meydan, Jacob L. Glass, Alan H. Shih, Ruud Delwel, Ross L. Levine, Christopher E. Mason, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2020) 10 (12): 1934–1949.
https://doi.org/10.1158/2159-8290.CD-19-0897
Published: 01 December 2020
View articletitled, Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML
Open the PDF for Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML in another window
Includes: Supplementary data
Journal Articles

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML

Cihangir Duy, Matt Teater, Francine E. Garrett-Bakelman, Tak C. Lee, Cem Meydan, Jacob L. Glass, Meng Li, Johannes C. Hellmuth, Helai P. Mohammad, Kimberly N. Smitheman, Alan H. Shih, Omar Abdel-Wahab, Martin S. Tallman, Monica L. Guzman, David Muench, H. Leighton Grimes, Gail J. Roboz, Ryan G. Kruger, Caretha L. Creasy, Elisabeth M. Paietta, Ross L. Levine, Martin Carroll, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2019) 9 (7): 872–889.
https://doi.org/10.1158/2159-8290.CD-19-0106
Published: 01 July 2019
View articletitled, Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML
Open the PDF for Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML in another window
Includes: Supplementary data
Journal Articles

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Jacob L. Glass, Duane Hassane, Bas J. Wouters, Hiroyoshi Kunimoto, Roberto Avellino, Francine E. Garrett-Bakelman, Olga A. Guryanova, Robert Bowman, Shira Redlich, Andrew M. Intlekofer, Cem Meydan, Tingting Qin, Mame Fall, Alicia Alonso, Monica L. Guzman, Peter J.M. Valk, Craig B. Thompson, Ross Levine, Olivier Elemento, Ruud Delwel, Ari Melnick, Maria E. Figueroa
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 868–883.
https://doi.org/10.1158/2159-8290.CD-16-1032
Published: 01 August 2017
View articletitled, Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers
Open the PDF for Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers in another window
Includes: Supplementary data
Journal Articles

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia

Alan H. Shih, Cem Meydan, Kaitlyn Shank, Francine E. Garrett-Bakelman, Patrick S. Ward, Andrew M. Intlekofer, Abbas Nazir, Eytan M. Stein, Kristina Knapp, Jacob Glass, Jeremy Travins, Kim Straley, Camelia Gliser, Christopher E. Mason, Katharine Yen, Craig B. Thompson, Ari Melnick, Ross L. Levine
Journal: Cancer Discovery
Cancer Discov (2017) 7 (5): 494–505.
https://doi.org/10.1158/2159-8290.CD-16-1049
Published: 30 April 2017
View articletitled, Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia
Open the PDF for Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas

Yanwen Jiang, Ana Ortega-Molina, Huimin Geng, Hsia-Yuan Ying, Katerina Hatzi, Sara Parsa, Dylan McNally, Ling Wang, Ashley S. Doane, Xabier Agirre, Matt Teater, Cem Meydan, Zhuoning Li, David Poloway, Shenqiu Wang, Daisuke Ennishi, David W. Scott, Kristy R. Stengel, Janice E. Kranz, Edward Holson, Sneh Sharma, James W. Young, Chi-Shuen Chu, Robert G. Roeder, Rita Shaknovich, Scott W. Hiebert, Randy D. Gascoyne, Wayne Tam, Olivier Elemento, Hans-Guido Wendel, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2017) 7 (1): 38–53.
https://doi.org/10.1158/2159-8290.CD-16-0975
Published: 05 January 2017
View articletitled, CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
Open the PDF for CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas in another window
Includes: Supplementary data