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Ari Melnick
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Journal Articles

Untangling the Role of Polycomb Complexes in Chemotherapy Resistance

Cihangir Duy, Ari Melnick
Journal: Cancer Discovery
Cancer Discov (2018) 8 (11): 1348–1351.
https://doi.org/10.1158/2159-8290.CD-18-1080
Published: 01 November 2018
View article titled, Untangling the Role of Polycomb Complexes in Chemotherapy Resistance
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Journal Articles

MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia

Fiona C. Brown, Eric Still, Richard P. Koche, Christina Y. Yim, Sumiko Takao, Paolo Cifani, Casie Reed, Shehana Gunasekera, Scott B. Ficarro, Peter Romanienko, Willie Mark, Craig McCarthy, Elisa de Stanchina, Mithat Gonen, Venkatraman Seshan, Patrick Bhola, Conor O'Donnell, Barbara Spitzer, Crystal Stutzke, Vincent-Philippe Lavallée, Josée Hébert, Andrei V. Krivtsov, Ari Melnick, Elisabeth M. Paietta, Martin S. Tallman, Anthony Letai, Guy Sauvageau, Gayle Pouliot, Ross Levine, Jarrod A Marto, Scott A. Armstrong, Alex Kentsis
Journal: Cancer Discovery
Cancer Discov (2018) 8 (4): 478–497.
https://doi.org/10.1158/2159-8290.CD-17-1271
Published: 01 April 2018
View article titled, MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia
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Includes: Supplementary data
Journal Articles

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Jacob L. Glass, Duane Hassane, Bas J. Wouters, Hiroyoshi Kunimoto, Roberto Avellino, Francine E. Garrett-Bakelman, Olga A. Guryanova, Robert Bowman, Shira Redlich, Andrew M. Intlekofer, Cem Meydan, Tingting Qin, Mame Fall, Alicia Alonso, Monica L. Guzman, Peter J.M. Valk, Craig B. Thompson, Ross Levine, Olivier Elemento, Ruud Delwel, Ari Melnick, Maria E. Figueroa
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 868–883.
https://doi.org/10.1158/2159-8290.CD-16-1032
Published: 01 August 2017
View article titled, Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers
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Includes: Supplementary data
Journal Articles

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia

Alan H. Shih, Cem Meydan, Kaitlyn Shank, Francine E. Garrett-Bakelman, Patrick S. Ward, Andrew M. Intlekofer, Abbas Nazir, Eytan M. Stein, Kristina Knapp, Jacob Glass, Jeremy Travins, Kim Straley, Camelia Gliser, Christopher E. Mason, Katharine Yen, Craig B. Thompson, Ari Melnick, Ross L. Levine
Journal: Cancer Discovery
Cancer Discov (2017) 7 (5): 494–505.
https://doi.org/10.1158/2159-8290.CD-16-1049
Published: 30 April 2017
View article titled, Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in <em>IDH2</em>- and <em>TET2</em>-Mutant Acute Myeloid Leukemia
Open the PDF for Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in <em>IDH2</em>- and <em>TET2</em>-Mutant Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

Ester Valls, Camille Lobry, Huimin Geng, Ling Wang, Mariano Cardenas, Martín Rivas, Leandro Cerchietti, Philmo Oh, Shao Ning Yang, Erin Oswald, Camille W. Graham, Yanwen Jiang, Katerina Hatzi, Xabier Agirre, Eric Perkey, Zhuoning Li, Wayne Tam, Kamala Bhatt, John P. Leonard, Patrick A. Zweidler-McKay, Ivan Maillard, Olivier Elemento, Weimin Ci, Iannis Aifantis, Ari Melnick
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (5): 506–521.
https://doi.org/10.1158/2159-8290.CD-16-1189
Published: 30 April 2017
View article titled, BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells
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Includes: Supplementary data
Journal Articles

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

Sara E. Meyer, Tingting Qin, David E. Muench, Kohei Masuda, Meenakshi Venkatasubramanian, Emily Orr, Lauren Suarez, Steven D. Gore, Ruud Delwel, Elisabeth Paietta, Martin S. Tallman, Hugo Fernandez, Ari Melnick, Michelle M. Le Beau, Scott Kogan, Nathan Salomonis, Maria E. Figueroa, H. Leighton Grimes
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (5): 501–515.
https://doi.org/10.1158/2159-8290.CD-16-0008
Published: 01 May 2016
View article titled, DNMT3A Haploinsufficiency Transforms <em>FLT3</em><sup>ITD</sup> Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia
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Includes: Supplementary data
Journal Articles

Mechanism-Based Epigenetic Chemosensitization Therapy of Diffuse Large B-Cell Lymphoma

Thomas Clozel, ShaoNing Yang, Rebecca L. Elstrom, Wayne Tam, Peter Martin, Matthias Kormaksson, Samprit Banerjee, Aparna Vasanthakumar, Biljana Culjkovic, David W. Scott, Sarah Wyman, Micheal Leser, Rita Shaknovich, Amy Chadburn, Fabrizio Tabbo, Lucy A. Godley, Randy D. Gascoyne, Katherine L. Borden, Giorgio Inghirami, John P. Leonard, Ari Melnick, Leandro Cerchietti
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (9): 1002–1019.
https://doi.org/10.1158/2159-8290.CD-13-0117
Published: 09 September 2013
View article titled, Mechanism-Based Epigenetic Chemosensitization Therapy of Diffuse Large B-Cell Lymphoma
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Includes: Supplementary data
Journal Articles

Discovering What Makes STAT Signaling TYK in T-ALL

Lorena Fontan, Ari Melnick
Journal: Cancer Discovery
Cancer Discov (2013) 3 (5): 494–496.
https://doi.org/10.1158/2159-8290.CD-13-0123
Published: 08 May 2013
View article titled, Discovering What Makes STAT Signaling TYK in T-ALL
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