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Antoine Hollebecque
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Journal Articles

Resistance to Selective FGFR Inhibitors in FGFR-Driven Urothelial Cancer

Francesco Facchinetti, Antoine Hollebecque, Floriane Braye, Damien Vasseur, Yoann Pradat, Rastislav Bahleda, Cédric Pobel, Ludovic Bigot, Olivier Déas, Juan David Florez Arango, Giorgia Guaitoli, Hayato Mizuta, David Combarel, Lambros Tselikas, Stefan Michiels, Sergey I. Nikolaev, Jean-Yves Scoazec, Santiago Ponce-Aix, Benjamin Besse, Ken A. Olaussen, Yohann Loriot, Luc Friboulet
Journal: Cancer Discovery
Cancer Discov (2023) 13 (9): 1998–2011.
https://doi.org/10.1158/2159-8290.CD-22-1441
Published: 06 September 2023
View article titled, Resistance to Selective FGFR Inhibitors in <em>FGFR-</em>Driven Urothelial Cancer
Open the PDF for Resistance to Selective FGFR Inhibitors in <em>FGFR-</em>Driven Urothelial Cancer in another window
Includes: Supplementary data
Journal Articles

Integrative Pan-Cancer Genomic and Transcriptomic Analyses of Refractory Metastatic Cancer

Yoann Pradat, Julien Viot, Andrey A. Yurchenko, Konstantin Gunbin, Luigi Cerbone, Marc Deloger, Guillaume Grisay, Loic Verlingue, Véronique Scott, Ismael Padioleau, Leonardo Panunzi, Stefan Michiels, Antoine Hollebecque, Gérôme Jules-Clément, Laura Mezquita, Antoine Lainé, Yohann Loriot, Benjamin Besse, Luc Friboulet, Fabrice André, Paul-Henry Cournède, Daniel Gautheret, Sergey I. Nikolaev
Journal: Cancer Discovery
Cancer Discov (2023) 13 (5): 1116–1143.
https://doi.org/10.1158/2159-8290.CD-22-0966
Published: 04 May 2023
View article titled, Integrative Pan-Cancer Genomic and Transcriptomic Analyses of Refractory Metastatic Cancer
Open the PDF for Integrative Pan-Cancer Genomic and Transcriptomic Analyses of Refractory Metastatic Cancer in another window
Includes: Supplementary data
Journal Articles

PD-1 Blockade in Solid Tumors with Defects in Polymerase Epsilon

Benoit Rousseau, Ivan Bieche, Eric Pasmant, Nadim Hamzaoui, Nicolas Leulliot, Lucas Michon, Aurelien de Reynies, Valerie Attignon, Michael B. Foote, Julien Masliah-Planchon, Magali Svrcek, Romain Cohen, Victor Simmet, Paule Augereau, David Malka, Antoine Hollebecque, Damien Pouessel, Carlos Gomez-Roca, Rosine Guimbaud, Amandine Bruyas, Marielle Guillet, Jean-Jacques Grob, Muriel Duluc, Sophie Cousin, Christelle de la Fouchardiere, Aude Flechon, Frederic Rolland, Sandrine Hiret, Esma Saada-Bouzid, Olivier Bouche, Thierry Andre, Diane Pannier, Farid El Hajbi, Stephane Oudard, Christophe Tournigand, Jean-Charles Soria, Stephane Champiat, Drew G. Gerber, Dennis Stephens, Michelle F. Lamendola-Essel, Steven B. Maron, Bill H. Diplas, Guillem Argiles, Asha R. Krishnan, Severine Tabone-Eglinger, Anthony Ferrari, Neil H. Segal, Andrea Cercek, Natalie Hoog-Labouret, Frederic Legrand, Clotilde Simon, Assia Lamrani-Ghaouti, Luis A. Diaz, Jr, Pierre Saintigny, Sylvie Chevret, Aurelien Marabelle
Journal: Cancer Discovery
Cancer Discov (2022) 12 (6): 1435–1448.
https://doi.org/10.1158/2159-8290.CD-21-0521
Published: 02 June 2022
View article titled, PD-1 Blockade in Solid Tumors with Defects in Polymerase Epsilon
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Includes: Multimedia, Supplementary data
Journal Articles

Clinicogenomic Analysis of FGFR2-Rearranged Cholangiocarcinoma Identifies Correlates of Response and Mechanisms of Resistance to Pemigatinib

Ian M. Silverman, Antoine Hollebecque, Luc Friboulet, Sherry Owens, Robert C. Newton, Huiling Zhen, Luis Féliz, Camilla Zecchetto, Davide Melisi, Timothy C. Burn
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (2): 326–339.
https://doi.org/10.1158/2159-8290.CD-20-0766
Published: 02 February 2021
View article titled, Clinicogenomic Analysis of <em>FGFR2</em>-Rearranged Cholangiocarcinoma Identifies Correlates of Response and Mechanisms of Resistance to Pemigatinib
Open the PDF for Clinicogenomic Analysis of <em>FGFR2</em>-Rearranged Cholangiocarcinoma Identifies Correlates of Response and Mechanisms of Resistance to Pemigatinib in another window
Includes: Supplementary data
Journal Articles

First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma

Richard D. Kim, Debashis Sarker, Tim Meyer, Thomas Yau, Teresa Macarulla, Joong-Won Park, Su Pin Choo, Antoine Hollebecque, Max W. Sung, Ho-Yeong Lim, Vincenzo Mazzaferro, Joerg Trojan, Andrew X. Zhu, Jung-Hwan Yoon, Sunil Sharma, Zhong-Zhe Lin, Stephen L. Chan, Sandrine Faivre, Lynn G. Feun, Chia-Jui Yen, Jean-Francois Dufour, Daniel H. Palmer, Josep M. Llovet, Melissa Manoogian, Meera Tugnait, Nicolas Stransky, Margit Hagel, Nancy E. Kohl, Christoph Lengauer, Cori Ann Sherwin, Oleg Schmidt-Kittler, Klaus P. Hoeflich, Hongliang Shi, Beni B. Wolf, Yoon-Koo Kang
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (12): 1696–1707.
https://doi.org/10.1158/2159-8290.CD-19-0555
Published: 02 December 2019
View article titled, First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma
Open the PDF for First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAFV600E-Mutant Colorectal Cancer

Ryan B. Corcoran, Thierry André, Chloe E. Atreya, Jan H.M. Schellens, Takayuki Yoshino, Johanna C. Bendell, Antoine Hollebecque, Autumn J. McRee, Salvatore Siena, Gary Middleton, Kei Muro, Michael S. Gordon, Josep Tabernero, Rona Yaeger, Peter J. O'Dwyer, Yves Humblet, Filip De Vos, A. Scott Jung, Jan C. Brase, Savina Jaeger, Severine Bettinger, Bijoyesh Mookerjee, Fatima Rangwala, Eric Van Cutsem
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (4): 428–443.
https://doi.org/10.1158/2159-8290.CD-17-1226
Published: 01 April 2018
View article titled, Combined BRAF, EGFR, and MEK Inhibition in Patients with <em>BRAF</em><sup>V600E</sup>-Mutant Colorectal Cancer
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Includes: Supplementary data
Journal Articles

High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial

Christophe Massard, Stefan Michiels, Charles Ferté, Marie-Cécile Le Deley, Ludovic Lacroix, Antoine Hollebecque, Loic Verlingue, Ecaterina Ileana, Silvia Rosellini, Samy Ammari, Maud Ngo-Camus, Rastislav Bahleda, Anas Gazzah, Andrea Varga, Sophie Postel-Vinay, Yohann Loriot, Caroline Even, Ingrid Breuskin, Nathalie Auger, Bastien Job, Thierry De Baere, Frederic Deschamps, Philippe Vielh, Jean-Yves Scoazec, Vladimir Lazar, Catherine Richon, Vincent Ribrag, Eric Deutsch, Eric Angevin, Gilles Vassal, Alexander Eggermont, Fabrice André, Jean-Charles Soria
Journal: Cancer Discovery
Cancer Discov (2017) 7 (6): 586–595.
https://doi.org/10.1158/2159-8290.CD-16-1396
Published: 01 June 2017
View article titled, High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial
Open the PDF for High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial in another window
Includes: Supplementary data