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Anna C. Obenauf
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Journal Articles

Zongertinib (BI 1810631), an Irreversible HER2 TKI, Spares EGFR Signaling and Improves Therapeutic Response in Preclinical Models and Patients with HER2-Driven Cancers

Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C. Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyová, Dirk Scharn, Mark A. Pearson, Johannes Popow, Anna C. Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L. Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John V. Heymach, Flavio Solca, Ralph A. Neumüller
Journal: Cancer Discovery
Cancer Discov (2025) 15 (1): 119–138.
https://doi.org/10.1158/2159-8290.CD-24-0306
Published: 13 January 2025
View article titled, Zongertinib (BI 1810631), an Irreversible HER2 TKI, Spares EGFR Signaling and Improves Therapeutic Response in Preclinical Models and Patients with HER2-Driven Cancers
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Includes: Supplementary data
Journal Articles

Cancer Evolution: A Multifaceted Affair

Giovanni Ciriello, Luca Magnani, Sarah J. Aitken, Leila Akkari, Sam Behjati, Douglas Hanahan, Dan A. Landau, Nuria Lopez-Bigas, Darío G. Lupiáñez, Jean-Christophe Marine, Ana Martin-Villalba, Gioacchino Natoli, Anna C. Obenauf, Elisa Oricchio, Paola Scaffidi, Andrea Sottoriva, Alexander Swarbrick, Giovanni Tonon, Sakari Vanharanta, Johannes Zuber
Journal: Cancer Discovery
Cancer Discov (2024) 14 (1): 36–48.
https://doi.org/10.1158/2159-8290.CD-23-0530
Published: 12 January 2024
View article titled, Cancer Evolution: A Multifaceted Affair
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Journal Articles

Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers

Lukas Leiendecker, Tobias Neumann, Pauline S. Jung, Shona M. Cronin, Thomas L. Steinacker, Alexander Schleiffer, Michael Schutzbier, Karl Mechtler, Thibault Kervarrec, Estelle Laurent, Kamel Bachiri, Etienne Coyaud, Rajmohan Murali, Klaus J. Busam, Babak Itzinger-Monshi, Reinhard Kirnbauer, Lorenzo Cerroni, Eduardo Calonje, Arno Rütten, Frank Stubenrauch, Klaus G. Griewank, Thomas Wiesner, Anna C. Obenauf
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 70–84.
https://doi.org/10.1158/2159-8290.CD-22-0489
Published: 09 January 2023
View article titled, Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
Open the PDF for Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers in another window
Includes: Supplementary data