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Alex Toker
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Journal Articles

The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

Hui Liu, Marcia N. Paddock, Haibin Wang, Charles J. Murphy, Renee C. Geck, Adrija J. Navarro, Gerburg M. Wulf, Olivier Elemento, Volker Haucke, Lewis C. Cantley, Alex Toker
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (8): 1226–1239.
https://doi.org/10.1158/2159-8290.CD-19-1262
Published: 03 August 2020
View articletitled, The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer
Open the PDF for The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer

Hui Liu, Charles J. Murphy, Florian A. Karreth, Kristina B. Emdal, Forest M. White, Olivier Elemento, Alex Toker, Gerburg M. Wulf, Lewis C. Cantley
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (3): 354–369.
https://doi.org/10.1158/2159-8290.CD-17-0679
Published: 01 March 2018
View articletitled, Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer
Open the PDF for Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer

Kristin K. Brown, Jessica B. Spinelli, John M. Asara, Alex Toker
Journal: Cancer Discovery
Cancer Discov (2017) 7 (4): 391–399.
https://doi.org/10.1158/2159-8290.CD-16-0611
Published: 02 April 2017
View articletitled, Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer
Open the PDF for Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex

Pengda Liu, Wenjian Gan, Y. Rebecca Chin, Kohei Ogura, Jianping Guo, Jinfang Zhang, Bin Wang, John Blenis, Lewis C. Cantley, Alex Toker, Bing Su, Wenyi Wei
Journal: Cancer Discovery
Cancer Discov (2015) 5 (11): 1194–1209.
https://doi.org/10.1158/2159-8290.CD-15-0460
Published: 01 November 2015
View articletitled, PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex
Open the PDF for PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex in another window
Includes: Supplementary data
Journal Articles

PTEN-Deficient Tumors Depend on AKT2 for Maintenance and Survival

Y. Rebecca Chin, Xin Yuan, Steven P. Balk, Alex Toker
Journal: Cancer Discovery
Cancer Discov (2014) 4 (8): 942–955.
https://doi.org/10.1158/2159-8290.CD-13-0873
Published: 03 August 2014
View articletitled, PTEN-Deficient Tumors Depend on AKT2 for Maintenance and Survival
Open the PDF for PTEN-Deficient Tumors Depend on AKT2 for Maintenance and Survival in another window
Includes: Supplementary data