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Alec C. Kimmelman
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Journal Articles

Metabolic Codependencies in the Tumor Microenvironment

Prasenjit Dey, Alec C. Kimmelman, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2021) 11 (5): 1067–1081.
https://doi.org/10.1158/2159-8290.CD-20-1211
Published: 01 May 2021
View articletitled, Metabolic Codependencies in the Tumor Microenvironment
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Journal Articles

Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer

Seth J. Parker, Caroline R. Amendola, Kate E.R. Hollinshead, Qijia Yu, Keisuke Yamamoto, Joel Encarnación-Rosado, Rebecca E. Rose, Madeleine M. LaRue, Albert S.W. Sohn, Doug E. Biancur, Joao A. Paulo, Steven P. Gygi, Drew R. Jones, Huamin Wang, Mark R. Philips, Dafna Bar-Sagi, Joseph D. Mancias, Alec C. Kimmelman
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (7): 1018–1037.
https://doi.org/10.1158/2159-8290.CD-19-0959
Published: 01 July 2020
View articletitled, Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Targeting Autophagy in Cancer: Recent Advances and Future Directions

Ravi K. Amaravadi, Alec C. Kimmelman, Jayanta Debnath
Journal: Cancer Discovery
Cancer Discov (2019) 9 (9): 1167–1181.
https://doi.org/10.1158/2159-8290.CD-19-0292
Published: 03 September 2019
View articletitled, Targeting Autophagy in Cancer: Recent Advances and Future Directions
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Journal Articles

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms

Annan Yang, Grit Herter-Sprie, Haikuo Zhang, Elaine Y. Lin, Douglas Biancur, Xiaoxu Wang, Jiehui Deng, Josephine Hai, Shenghong Yang, Kwok-Kin Wong, Alec C. Kimmelman
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (3): 276–287.
https://doi.org/10.1158/2159-8290.CD-17-0952
Published: 01 March 2018
View articletitled, Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms
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Includes: Supplementary data
Journal Articles

Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations

Annan Yang, N.V. Rajeshkumar, Xiaoxu Wang, Shinichi Yabuuchi, Brian M. Alexander, Gerald C. Chu, Daniel D. Von Hoff, Anirban Maitra, Alec C. Kimmelman
Journal: Cancer Discovery
Cancer Discov (2014) 4 (8): 905–913.
https://doi.org/10.1158/2159-8290.CD-14-0362
Published: 03 August 2014
View articletitled, Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
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Includes: Supplementary data
Journal Articles

PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network

Haoqiang Ying, Kutlu G. Elpek, Anant Vinjamoori, Stephanie M. Zimmerman, Gerald C. Chu, Haiyan Yan, Eliot Fletcher-Sananikone, Hailei Zhang, Yingchun Liu, Wei Wang, Xiaojia Ren, Hongwu Zheng, Alec C. Kimmelman, Ji-hye Paik, Carol Lim, Samuel R. Perry, Shan Jiang, Brian Malinn, Alexei Protopopov, Simona Colla, Yonghong Xiao, Aram F. Hezel, Nabeel Bardeesy, Shannon J. Turley, Y. Alan Wang, Lynda Chin, Sarah P. Thayer, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2011) 1 (2): 158–169.
https://doi.org/10.1158/2159-8290.CD-11-0031
Published: 17 July 2011
View articletitled, PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
Open the PDF for PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network in another window
Includes: Supplementary data