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Article Commentary May 20 2022
A Digital Breast Tomosynthesis Risk Model Can Guide Clinical Care in Breast Cancer
Cancer Discov (2022)
Article Commentary May 20 2022
Lymph Node Metastasis Induces Immune Tolerance and Distant Metastasis
Cancer Discov (2022)
Article Commentary May 20 2022
IL6 Blockade Reduces Immunotherapy-Induced Immune-Related Adverse Events
Cancer Discov (2022)
Article Commentary May 20 2022
Hotspot Mutations Optimize the Oncogenic–Immunogenic Trade-off
Cancer Discov (2022)
Article Commentary May 20 2022
Combination Vistusertib and Anastrozole Shows Benefit in Endometrial Cancer
Cancer Discov (2022)
News May 19 2022
Break Through Cancer Doles Out $50M
Cancer Discov (2022)
News May 18 2022
Of Mammals and Mutations, Life Span, Cancer Risk
Cancer Discov (2022)
Research Article May 13 2022
Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C
Cancer Discov (2022)
Research Article May 13 2022
The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution
Cancer Discov (2022)
Article Commentary May 13 2022
apCAFs Are Derived from Mesothelial Cells and Induce Regulatory T Cells
Cancer Discov (2022)
Article Commentary May 13 2022
Colorectal Cancer Growth Is Reduced by the Ketone Body β-Hydroxybutyrate
Cancer Discov (2022)
Article Commentary May 13 2022
Tumor-Resilient T-cell Signature Predicts Immunotherapy Response
Cancer Discov (2022)
Article Commentary May 13 2022
Intermittent PI3Kδ Inhibition Mitigates Immune-Related Adverse Events
Cancer Discov (2022)
Article Commentary May 13 2022
CCL22 Mutations Promote NK-cell Lymphoproliferative Disease
Cancer Discov (2022)
Article Commentary May 13 2022
Chemical Proteomics Reveals MBLAC2 as a Major Off-Target of HDAC Inhibitors
Cancer Discov (2022)
News May 13 2022
FDA Aims to Ban Menthol in Cigarettes
Cancer Discov (2022)
Research Article May 12 2022
Tumor-derived Lysophosphatidic Acid Blunts Protective Type-I Interferon Responses in Ovarian Cancer
Cancer Discov candisc.1181.2021.
News May 12 2022
Bempeg Failure Unlikely to Affect Other IL2 Agents
Cancer Discov (2022)
Research Article May 12 2022
Sequential single cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin's lymphoma
Cancer Discov candisc.1586.2021.
Research Article May 11 2022
Longitudinal Undetectable Molecular Residual Disease Defines Potentially Cured Population in Localized Non–Small Cell Lung Cancer
Cancer Discov (2022)
Research Article May 11 2022
PD-1 Blockade in Solid Tumors with Defects in Polymerase Epsilon
Cancer Discov (2022)
Research Article May 11 2022
Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse
Cancer Discov (2022)
Research Article May 11 2022
Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
Cancer Discov (2022)
Research Article May 10 2022
Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
Cancer Discov candisc.0680.2021.
News May 9 2022
Ivosidenib Boosts Azacitidine's Effectiveness in AML
Cancer Discov (2022)
Research Article May 6 2022
Temozolomide treatment alters mismatch repair and boosts mutational burden in tumor and blood of colorectal cancer patients
Cancer Discov candisc.1434.2021.
Article Commentary May 6 2022
Targeting Mitochondrial Apoptosis Improves NK cell–Based Immunotherapies
Cancer Discov (2022)
Article Commentary May 6 2022
Cancer Cells Induce Delayed DNA Breaks to Resist Radiation Therapy
Cancer Discov (2022)
Article Commentary May 6 2022
A Patient-Derived Organoid Screen Identified the Bispecific Antibody MCLA-158
Cancer Discov (2022)
Article Commentary May 6 2022
RIPK1 Promotes Intrinsic and Extrinsic Resistance to Immunotherapy
Cancer Discov (2022)
Article Commentary May 6 2022
Ceramide Accumulation Induces the Integrated Stress Response in AML
Cancer Discov (2022)
Article Commentary May 6 2022
CCNE1 Amplification and PKMYT1 Inhibition Are Synthetic Lethal
Cancer Discov (2022)
Article Commentary May 6 2022
A Self-reactive Innate-like T-cell Program Was Identified in Cancer Immunity
Cancer Discov (2022)
Research Article May 4 2022
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer
Cancer Discov (2022)
Research Article May 3 2022
Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Cancer Discov (2022)
News May 3 2022
Mechanism Found for IDO1 Inhibitor Evasion
Cancer Discov (2022)
Research Article May 2 2022
MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
Cancer Discov candisc.0646.2021.
Research Article May 2 2022
Precision Combination Therapies Based on Recurrent Oncogenic Coalterations
Cancer Discov (2022)
Research Article April 29 2022
Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML
Cancer Discov (2022)
Article Commentary April 29 2022
ESCRT Protein Inhibition Enhances CTL-Mediated Cytolysis of Tumor Cells
Cancer Discov (2022)
Article Commentary April 29 2022
Quiescent Breast Cancer Cells Are Resistant to T-cell Killing
Cancer Discov (2022)
News April 29 2022
Driving CAR T Cells against Solid Tumors
Cancer Discov (2022)
Article Commentary April 29 2022
CAR T-cell Efficacy in Solid Tumors Is Enhanced by Oncolytic Viruses
Cancer Discov (2022)
Article Commentary April 29 2022
Addition of Nintedanib to Neoadjuvant Chemotherapy Is Safe in Bladder Cancer
Cancer Discov (2022)
Article Commentary April 29 2022
Navicixizumab plus Paclitaxel Shows Clinical Benefit in Platinum-Resistant Ovarian Cancer
Cancer Discov (2022)
News April 27 2022
Cancer Diagnosis, Treatment Linked to Suicide Risk
Cancer Discov (2022)
Article Commentary April 22 2022
IFNγR Pathway Mediates CAR T Cell Cytotoxicity Against Solid Tumors
Cancer Discov (2022)
Article Commentary April 22 2022
Intratumor Microbes Promote Murine Breast Cancer Cell Invasion
Cancer Discov (2022)
Article Commentary April 22 2022
Somatic Mutation Events Were Characterized Across the Whole Cancer Genome
Cancer Discov (2022)
Article Commentary April 22 2022
Oxidative Stress in Skeletal Muscle Hinders Metastatic Colonization
Cancer Discov (2022)
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