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Precision Medicine and Therapeutic Resistance Collection

Cancer Discovery publishes high-impact, peer-reviewed articles describing major advances in research and clinical trials. As the premier cancer information resource, the Journal also presents Review Articles, Perspectives and Commentaries, News stories, and Research Watch summaries of important journal articles to its readers to keep them informed about the latest findings in the field. Topics span the spectrum of cancer research and medicine from the laboratory to the clinic and epidemiologic studies

The Cancer Discovery editors proudly present this collection of abstracts from impactful precision medicine research articles selected from the Journal. Some of these select original research articles are followed by their corresponding In the Spotlight commentaries, which serve to place them in the context of their field.

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Diana M. Carvalho; Peter J. Richardson; Nagore Olaciregui; Reda Stankunaite; Cinzia Lavarino; Valeria Molinari; Elizabeth A. Corley; Daniel P. Smith; Ruth Ruddle; Adam Donovan; Akos Pal; Florence I. Raynaud; Sara Temelso; Alan Mackay; John P. Overington; Anne Phelan; David Sheppard; Andrew Mackinnon; Bassel Zebian; Safa Al-Sarraj; Ashirwad Merve; Jeremy Pryce; Jacques Grill; Michael Hubank; Ofelia Cruz; Andres Morales La Madrid; Sabine Mueller; Angel M. Carcaboso; Fernando Carceller; Chris Jones
Doi: 10.1158/2159-8290.CD-20-1201
Disha Malani; Ashwini Kumar; Oscar Brück; Mika Kontro; Bhagwan Yadav; Monica Hellesøy; Heikki Kuusanmäki; Olli Dufva; Matti Kankainen; Samuli Eldfors; Swapnil Potdar; Jani Saarela; Laura Turunen; Alun Parsons; Imre Västrik; Katja Kivinen; Janna Saarela; Riikka Räty; Minna Lehto; Maija Wolf; Bjorn Tore Gjertsen; Satu Mustjoki; Tero Aittokallio; Krister Wennerberg; Caroline A. Heckman; Olli Kallioniemi; Kimmo Porkka
Doi: 10.1158/2159-8290.CD-21-0410
Christoph Kornauth; Tea Pemovska; Gregory I. Vladimer; Günther Bayer; Michael Bergmann; Sandra Eder; Ruth Eichner; Martin Erl; Harald Esterbauer; Ruth Exner; Verena Felsleitner-Hauer; Maurizio Forte; Alexander Gaiger; Klaus Geissler; Hildegard T. Greinix; Wolfgang Gstöttner; Marcus Hacker; Bernd Lorenz Hartmann; Alexander W. Hauswirth; Tim Heinemann; Daniel Heintel; Mir Alireza Hoda; Georg Hopfinger; Ulrich Jaeger; Lukas Kazianka; Lukas Kenner; Barbara Kiesewetter; Nikolaus Krall; Gerhard Krajnik; Stefan Kubicek; Trang Le; Simone Lubowitzki; Marius E. Mayerhoefer; Elisabeth Menschel; Olaf Merkel; Katsuhiro Miura; Leonhard Müllauer; Peter Neumeister; Thomas Noesslinger; Katharina Ocko; Leopold Öhler; Michael Panny; Alexander Pichler; Edit Porpaczy; Gerald W. Prager; Markus Raderer; Robin Ristl; Reinhard Ruckser; Julius Salamon; Ana-Iris Schiefer; Ann-Sofie Schmolke; Ilse Schwarzinger; Edgar Selzer; Christian Sillaber; Cathrin Skrabs; Wolfgang R. Sperr; Ismet Srndic; Renate Thalhammer; Peter Valent; Emiel van der Kouwe; Katrina Vanura; Stefan Vogt; Cora Waldstein; Dominik Wolf; Christoph C. Zielinski; Niklas Zojer; Ingrid Simonitsch-Klupp; Giulio Superti-Furga; Berend Snijder; Philipp B. Staber
Doi: 10.1158/2159-8290.CD-21-0538
Funda Meric-Bernstam; Rastislav Bahleda; Cinta Hierro; Marc Sanson; John Bridgewater; Hendrik-Tobias Arkenau; Ben Tran; Robin Kate Kelley; Joon Oh Park; Milind Javle; Yaohua He; Karim A. Benhadji; Lipika Goyal
Doi: 10.1158/2159-8290.CD-21-0697
Anthony Letai
Doi: 10.1158/2159-8290.CD-21-1498
Sun Min Lim; Chang Gon Kim; Jii Bum Lee; Byoung Chul Cho
Doi: 10.1158/2159-8290.CD-21-1429
Pasi A. Jänne; Christina Baik; Wu-Chou Su; Melissa L. Johnson; Hidetoshi Hayashi; Makoto Nishio; Dong-Wan Kim; Marianna Koczywas; Kathryn A. Gold; Conor E. Steuer; Haruyasu Murakami; James Chih-Hsin Yang; Sang-We Kim; Michele Vigliotti; Rong Shi; Zhenhao Qi; Yang Qiu; Lihui Zhao; David Sternberg; Channing Yu; Helena A. Yu
Doi: 10.1158/2159-8290.CD-21-0715
Alexander Eggermont; Birgit Geoerger; Giuseppe Curigliano
Doi: 10.1158/2159-8290.CD-21-1069
Kanwal Raghav; Suyu Liu; Michael J. Overman; Anneleis F. Willett; Mark Knafl; Szu-Chin Fu; Anais Malpica; Seema Prasad; Richard E. Royal; Christopher P. Scally; Paul F. Mansfield; Ignacio I. Wistuba; Andrew P. Futreal; Dipen M. Maru; Luisa M. Solis Soto; Edwin R. Parra Cuentas; Honglei Chen; Pamela Villalobos; Anuj Verma; Armeen Mahvash; Patrick Hwu; Patricia Cortazar; Edward McKenna; Cindy Yun; Shannon Dervin; Katja Schulze; Walter C. Darbonne; Ajaykumar C. Morani; Scott Kopetz; Keith F. Fournier; Scott E. Woodman; James C. Yao; Gauri R. Varadhachary; Daniel M. Halperin
Doi: 10.1158/2159-8290.CD-21-0331
Philippe Aftimos; Mafalda Oliveira; Alexandre Irrthum; Debora Fumagalli; Christos Sotiriou; Einav Nili Gal-Yam; Mark E. Robson; Justin Ndozeng; Angelo Di Leo; Eva M. Ciruelos; Evandro de Azambuja; Giuseppe Viale; Elsemieke D. Scheepers; Giuseppe Curigliano; Judith M. Bliss; Jorge S. Reis-Filho; Marco Colleoni; Marija Balic; Fatima Cardoso; Joan Albanell; Caroline Duhem; Sandrine Marreaud; Dario Romagnoli; Beatriz Rojas; Andrea Gombos; Hans Wildiers; Angel Guerrero-Zotano; Peter Hall; Andrea Bonetti; Karolina Fs Larsson; Martina Degiorgis; Silvia Khodaverdi; Richard Greil; Ásgerdur Sverrisdóttir; Marta Paoli; Ethel Seyll; Sibylle Loibl; Barbro Linderholm; Gabriele Zoppoli; Nancy E. Davidson; Oskar Th Johannsson; Philippe L. Bedard; Sherene Loi; Susan Knox; David A. Cameron; Nadia Harbeck; Maite Lasa Montoya; Mariana Brandão; Andrea Vingiani; Carmela Caballero; Florentine S. Hilbers; Lucy R. Yates; Matteo Benelli; David Venet; Martine J. Piccart
Doi: 10.1158/2159-8290.CD-20-1647
Peter Horak; Christoph Heining; Simon Kreutzfeldt; Barbara Hutter; Andreas Mock; Jennifer Hüllein; Martina Fröhlich; Sebastian Uhrig; Arne Jahn; Andreas Rump; Laura Gieldon; Lino Möhrmann; Dorothea Hanf; Veronica Teleanu; Christoph E. Heilig; Daniel B. Lipka; Michael Allgäuer; Leo Ruhnke; Andreas Laßmann; Volker Endris; Olaf Neumann; Roland Penzel; Katja Beck; Daniela Richter; Ulrike Winter; Stephan Wolf; Katrin Pfütze; Christina Geörg; Bettina Meißburger; Ivo Buchhalter; Marinela Augustin; Walter E. Aulitzky; Peter Hohenberger; Matthias Kroiss; Peter Schirmacher; Richard F. Schlenk; Ulrich Keilholz; Frederick Klauschen; Gunnar Folprecht; Sebastian Bauer; Jens Thomas Siveke; Christian H. Brandts; Thomas Kindler; Melanie Boerries; Anna L. Illert; Nikolas von Bubnoff; Philipp J. Jost; Karsten Spiekermann; Michael Bitzer; Klaus Schulze-Osthoff; Christof von Kalle; Barbara Klink; Benedikt Brors; Albrecht Stenzinger; Evelin Schröck; Daniel Hübschmann; Wilko Weichert; Hanno Glimm; Stefan Fröhling
Doi: 10.1158/2159-8290.CD-21-0126
Mihaela Aldea; Jose Carlos Benitez; Nathalie Chaput; Benjamin Besse
Doi: 10.1158/2159-8290.CD-21-1046
Cornelis M. van Tilburg; Elke Pfaff; Kristian W. Pajtler; Karin P.S. Langenberg; Petra Fiesel; Barbara C. Jones; Gnana Prakash Balasubramanian; Sebastian Stark; Pascal D. Johann; Mirjam Blattner-Johnson; Kathrin Schramm; Nicola Dikow; Steffen Hirsch; Christian Sutter; Kerstin Grund; Arend von Stackelberg; Andreas E. Kulozik; Andrej Lissat; Arndt Borkhardt; Roland Meisel; Dirk Reinhardt; Jan-Henning Klusmann; Gudrun Fleischhack; Stephan Tippelt; Dietrich von Schweinitz; Irene Schmid; Christof M. Kramm; André O. von Bueren; Gabriele Calaminus; Peter Vorwerk; Norbert Graf; Frank Westermann; Matthias Fischer; Angelika Eggert; Birgit Burkhardt; Wilhelm Wößmann; Michaela Nathrath; Stefanie Hecker-Nolting; Michael C. Frühwald; Dominik T. Schneider; Ines B. Brecht; Petra Ketteler; Simone Fulda; Ewa Koscielniak; Michael T. Meister; Monika Scheer; Simone Hettmer; Matthias Schwab; Roman Tremmel; Ingrid Øra; Caroline Hutter; Nicolas U. Gerber; Olli Lohi; Bernarda Kazanowska; Antonis Kattamis; Maria Filippidou; Bianca Goemans; C. Michel Zwaan; Till Milde; Natalie Jäger; Stephan Wolf; David Reuss; Felix Sahm; Andreas von Deimling; Uta Dirksen; Angelika Freitag; Ruth Witt; Peter Lichter; Annette Kopp-Schneider; David T.W. Jones; Jan J. Molenaar; David Capper; Stefan M. Pfister; Olaf Witt
Doi: 10.1158/2159-8290.CD-21-0094
Prasad S. Adusumilli; Marjorie G. Zauderer; Isabelle Rivière; Stephen B. Solomon; Valerie W. Rusch; Roisin E. O'Cearbhaill; Amy Zhu; Waseem Cheema; Navin K. Chintala; Elizabeth Halton; John Pineda; Rocio Perez-Johnston; Kay See Tan; Bobby Daly; Jose A. Araujo Filho; Daniel Ngai; Erin McGee; Alain Vincent; Claudia Diamonte; Jennifer L. Sauter; Shanu Modi; Devanjan Sikder; Brigitte Senechal; Xiuyan Wang; William D. Travis; Mithat Gönen; Charles M. Rudin; Renier J. Brentjens; David R. Jones; Michel Sadelain
Doi: 10.1158/2159-8290.CD-21-0407
James T. Coates; Sheng Sun; Ignaty Leshchiner; Nayana Thimmiah; Elizabeth E. Martin; Daniel McLoughlin; Brian P. Danysh; Kara Slowik; Raquel A. Jacobs; Kahn Rhrissorrakrai; Filippo Utro; Chaya Levovitz; Elyssa Denault; Charlotte S. Walmsley; Avinash Kambadakone; James R. Stone; Steven J. Isakoff; Laxmi Parida; Dejan Juric; Gad Getz; Aditya Bardia; Leif W. Ellisen
Doi: 10.1158/2159-8290.CD-21-0702
Noritaka Tanaka; Jessica J. Lin; Chendi Li; Meagan B. Ryan; Junbing Zhang; Lesli A. Kiedrowski; Alexa G. Michel; Mohammed U. Syed; Katerina A. Fella; Mustafa Sakhi; Islam Baiev; Dejan Juric; Justin F. Gainor; Samuel J. Klempner; Jochen K. Lennerz; Giulia Siravegna; Liron Bar-Peled; Aaron N. Hata; Rebecca S. Heist; Ryan B. Corcoran
Doi: 10.1158/2159-8290.CD-21-0365
Marika Pinnelli; Livio Trusolino
Doi: 10.1158/2159-8290.CD-21-0609
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