Noted

Sanofi will buy Kadmon Holdings for $1.9 billion. Sanofi will gain belumosudil (Rezurock), a ROCK2 inhibitor approved earlier this year for certain patients with chronic graft-versus-host disease. Kadmon's pipeline also includes therapies for immune and fibrotic diseases, as well as cancer immunotherapies.

The U.S. Court of Appeals for the Federal Circuit reversed a $1.2 billion ruling against Gilead for patent infringement. Bristol Myers Squibb (BMS) claimed that the chimeric antigen receptor (CAR) T-cell therapy axicabtagene ciloleucel (Yescarta) developed by Gilead subsidiary Kite Pharma infringed on a CAR T-cell patent held by BMS subsidiary Juno Therapeutics.

The FDA granted two approvals to zanubrutinib (Brukinsa; BeiGene)—for patients with Waldenström macroglobulinemia and for patients with relapsed/refractory marginal zone lymphoma who have received at least one anti-CD20 therapy. The drug was previously approved for mantle cell lymphoma.

Also, the agency authorized the marketing of software to assist pathologists in detecting prostate cancer. Paige Prostate is the first artificial intelligence–based software designed to identify areas on biopsy images that could be cancerous and flag them. On average, the software improved pathologists' detection of cancer by 7.3% compared with pathologists' analyses alone.

Survey results presented at the International Association for the Study of Lung Cancer 2021 World Conference on Lung Cancer revealed that almost two thirds of thoracic oncologists used telehealth for the first time during the COVID-19 pandemic. Oncologists reported that the top advantages of telehealth were continuity of care and maintenance of contact with patients.

New York, NY's Memorial Sloan Kettering Cancer Center announced the establishment of a center focused on patients ages 15 to 39, a group that often faces special treatment and psychosocial needs. The center will address underrepresentation of these patients in clinical trials, offer family planning and fertility services, tailor treatment to tumor biology, and make use of social media.

For more news on cancer research, visit Cancer Discovery online at http://cancerdiscovery.aacrjournals.org/CDNews.