• Fred Hutchinson Cancer Research Center and the Uganda Cancer Institute have broken ground on the first comprehensive cancer center jointly constructed by U.S. and African institutions in sub-Saharan Africa. The collaboration aims to increase survival rates for common infection-caused cancers from 10% to 90% over the next 3 years while researching new ways to prevent those cancers.

  • Exelixis Inc.'s cabozantinib more than doubled survival time for patients with advanced medullary thyroid cancer in a trial with 315 patients whose cancer had progressed, was inoperable, or had metastasized. The company says that patients who received the drug had median survival of 11 months before death or disease progression, compared to 4 months for patients given a placebo.

  • Analysis of more than 10,000 breast cancer patients in 17 trials worldwide shows that following breast-conserving surgery, radiotherapy almost halves 10-year risk of recurrence and reduces 15-year risk of mortality by a sixth. The report from the Early Breast Cancer Trialists' Collaborative Group was published in The Lancet.

  • Over the next decade, the population of U.S. cancer survivors over 65 years of age will increase by approximately 42%, to about 11 million, according to a study in Cancer Epidemiology, Biomarkers & Prevention. “We're seeing yet another effect of the baby boom generation and we need to prepare for this increase,” noted senior author Julia Rowland, PhD, director of the Office of Cancer Survivorship in NCI's Division of Cancer Control and Population Sciences.

  • Interviewing 28 cancer researchers about the process of cancer metastasis, researchers at the University of Chicago found ubiquitous disagreement around assumptions in any model of metastasis, according to their report in PLoS Computational Biology.

  • Complete Genomics, working with the Scripps Health system in San Diego, is funding and gathering whole-genome sequences for 1,000 elderly people in the “Wellderly Study,” which examines people from ages 80 through 108 years without any major diseases or long-term health complications.

For more news on cancer research, visit Cancer Discovery online at www.AACR.org/CDnews.