Marcia McNutt, PhD, took over as editor-in-chief of Science on June 1. The first woman to hold this role since the journal's inception in 1880, she succeeds Bruce Alberts, PhD. McNutt formerly served as director of the U.S. Geological Survey. A former professor of geophysics at Massachusetts Institute of Technology in Cambridge, she has also served as president and CEO of the Monterey Bay Aquarium Research Institute in Moss Landing, CA.

Jeremy Farrar, MBBS, DPhil, a clinical scientist and infectious disease researcher, has been appointed director of the Wellcome Trust in London, UK, effective October 1. He succeeds Sir Mark Walport, PhD, MB BChir. A professor of tropical medicine and global health, Farrar has been director of the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam, since 1996. In addition, he serves on several World Health Organization advisory committees. The Wellcome Trust is a global charity that contributes more than $1 billion annually to biomedical research.

Sir David Lane, PhD, joined the Ludwig Institute of Cancer Research in New York, NY, as its scientific director on June 1. Lane is also the chief scientist for Singapore's Agency for Science, Technology, and Research (A*STAR). He will divide his time between A*STAR and Ludwig, coordinating his new organization's global cancer research efforts.

Lane is credited with discovering the p53 protein, a vital tumor suppressor that is faulty in about half of human cancers. His current work focuses on controlling p53 and identifying targets for therapies that might restore its normal function.

For more news on cancer research, visit Cancer Discovery online at http://CDnews.aacrjournals.org.