A Chemically Remodeled Cellular Chaperone Targets Active State Mutant KRAS

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Research Watch| August 25 2023

Online ISSN: 2159-8290

Print ISSN: 2159-8274

2023

American Association for Cancer Research

Cancer Discov OF1.

https://doi.org/10.1158/2159-8290.CD-RW2023-134

Abstract

Formation of the CYPA:compound:KRAS^G12C tricomplex inhibits oncogenic signaling and tumor progression.

2023

American Association for Cancer Research

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