Aneuploidy, an imbalance in chromosome number, is a hallmark of human cancers with chromosomal instability, and it remains a major therapeutic challenge. In this issue, Ippolito and colleagues identify RNA and protein turnover as targetable therapeutic vulnerabilities in aneuploid cancers.

See related article by Ippolito et al., p. 2532

©2024 American Association for Cancer Research
2024
American Association for Cancer Research
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