Myeloid-Derived Itaconate Suppresses Antitumor Immunity

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Research Watch| February 06 2023

Online ISSN: 2159-8290

Print ISSN: 2159-8274

2023

American Association for Cancer Research

Cancer Discov (2023) 13 (2): 255.

Abstract

Itaconate secreted by MDSCs suppresses CD8⁺ T-cell effector function and promotes tumor growth.

2023

American Association for Cancer Research

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