Researchers have used the bacterium Listeria monocytogenes to deliver tetanus toxoid to mice with pancreatic ductal adenocarcinoma. In these mice, previously vaccinated for tetanus, memory T cells were reactivated to subsequently destroy the tumors. Plans are underway to evaluate this approach in a phase I trial.

©2022 American Association for Cancer Research
2022
American Association for Cancer Research
You do not currently have access to this content.