According to results from the phase III INTRIGUE trial, ripretinib is not superior to sunitinib as a second-line tyrosine kinase inhibitor for patients with gastrointestinal stromal tumors in terms of progression-free survival. However, ripretinib had a better safety profile and induced fewer grade 3–4 toxicities, including hypertension.

©2022 American Association for Cancer Research.
2022
American Association for Cancer Research.
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