Specific Helical Domain Contacts Mediate PARP1 Inhibitor Activity

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Research Watch| June 01 2020

Online ISSN: 2159-8290

Print ISSN: 2159-8274

2020

American Association for Cancer Research.

Cancer Discov (2020) 10 (6): 758.

Abstract

PARP1 inhibitors that clash with a specific helix in the helical domain prevent release from DNA.

2020

American Association for Cancer Research.

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