See article, p. 783.
Patients with cancer tend to be more susceptible to infections, but whether this is the case and how it may manifest in the context of COVID-19 has been addressed only in small studies. In a fourteen-center study in Wuhan, China—the epicenter of the outbreak—Dai and colleagues investigated the relationship between COVID-19 and cancer in 105 patients with cancer and 536 age-matched control patients, all with confirmed COVID-19. Consistent with a smaller study, patients with cancer had worse outcomes (defined as death, ICU admission, presence of one or more severe or critical symptoms, or need for invasive mechanical ventilation) than control patients on average. Cancer stage was a strong predictor of outcome: Patients with stage IV cancer had much higher rates of poor outcomes, whereas COVID-19 severity in patients with nonmetastatic cancer did not differ from severity in patients without cancer. There was also a notable...