Summary:

Song and colleagues describe how N-glycans stabilize expression of checkpoint molecule B7-H4 that suppresses T-cell function. Inhibiting N-glycan stabilization of B7-H4 generates an immune hot cancer that is more responsive to combination therapies.

See related article by Song et al., p. 1872.

©2020 American Association for Cancer Research.
2020
American Association for Cancer Research.
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