See article, p. 1465.

COVID-19 is particularly dangerous for patients with cancer, but information about individual factors associated with clinical outcome in patients with simultaneous COVID-19 and cancer is generally lacking. In an observational study of 890 patients from 19 centers in four European countries, Pinato and colleagues identified several risk factors for death from COVID-19 in patients with cancer. In agreement with findings from the general population, male sex, age greater than or equal to 65 years, and presence of two or more comorbidities other than cancer (most commonly hypertension, cardiovascular diseases, or diabetes mellitus) were all independently associated with greater risk of death. Active cancer (as opposed to cancer in remission) and advanced-stage cancer were independently associated with higher risk of death. Ongoing cancer treatment with chemotherapy, immunotherapy, endocrine therapy, or targeted therapy was not associated with increased risk of death; however, a possible confounder is that...

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