Cheung and colleagues identify PIK3R1 and PIK3R2, the genes encoding the α and β isoforms of the phosphatidylinositol 3-kinase (PI3K) p85 regulatory subunit, as additional mutation targets in endometrial cancer, and describe a novel mechanism leading to PTEN loss. Cancer Discovery; 1(2); 106–7. ©2011 AACR.

Commentary on Cheung et al., p. 170

©2011 American Association for Cancer Research.
2011
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