Cancer Discovery | American Association for Cancer Research

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Current Issue

Volume 14,

Issue 10

1 October 2024

About the Journal

Cancer Discovery publishes high-impact articles featuring major advances in research and clinical trials. Topics span the spectrum of cancer research and medicine from the laboratory to the clinic to epidemiologic studies. The journal also publishes News and Research Watch sections.Read More About the Journal

Editors-in-Chief

Lewis C. Cantley
Luis A. Diaz

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Impact Factor

30.6

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Featured Articles

The Epigenetic Hallmarks of Cancer

Manel Esteller; Mark A. Dawson; Cigall Kadoch; Feyruz V. Rassool; Peter A. Jones; Stephen B. Baylin

T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study

Justin F. Gainor, et al.

The N⁶-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma

Shiyan Wang, et al.

News

| October 09 2024

Nobel-Winning AI Advances Are Transforming Cancer Research

The Nobel Prize in Physics was awarded to John Hopfield, PhD, and Geoffrey Hinton, PhD, for their pioneering work in artificial neural networks, which laid the foundation for modern AI applications in cancer research. Their contributions have ...

Breaking

| October 11 2024

Gene Therapy Causes Cancer in Some Children

Seven out of the 67 children who received a gene therapy for a devastating neurologic disorder developed blood cancer ( N Engl J Med 2024 Oct 9 [Epub ahead of print] ). The therapy, elivaldogene autotemcel (Skysona; Bluebird Bio), consists of stem ...

Research Watch

| October 10 2024

Epigenetic Modification of Centromeric RNA Supports Genomic Stability

Major Finding: m 6 A modification of centromeric RNA (cenRNA) mediates CENPA binding and promotes cancer genomic stability. Concept: Leu61 and Arg63 of CENPA interact with m 6 A-modified cenRNA to support cancer cell proliferation. Impact: ...

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The article titled, Ironing Out the Kinks: Arming Natural Killer Cells against Ovarian Cancer., has an Alt Metric Attention Score of 2.95. Click to see more of this article's metrics.

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