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Steven A. Carr
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Journal Articles

BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes

Eva J. Schaefer, Helen C. Wang, Hannah Q. Karp, Clifford A. Meyer, Paloma Cejas, Micah D. Gearhart, Emmalee R. Adelman, Iman Fares, Annie Apffel, Klothilda Lim, Yingtian Xie, Christopher J. Gibson, Monica Schenone, H. Moses Murdock, Eunice S. Wang, Lukasz P. Gondek, Martin P. Carroll, Rahul S. Vedula, Eric S. Winer, Jacqueline S. Garcia, Richard M. Stone, Marlise R. Luskin, Steven A. Carr, Henry W. Long, Vivian J. Bardwell, Maria E. Figueroa, R. Coleman Lindsley
Journal: Blood Cancer Discovery
Blood Cancer Discov (2022) 3 (2): 116–135.
https://doi.org/10.1158/2643-3230.BCD-21-0115
Published: 01 March 2022
View article titled, <em>BCOR</em> and <em>BCORL1</em> Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
Open the PDF for <em>BCOR</em> and <em>BCORL1</em> Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes in another window
Includes: Supplementary data
Journal Articles

ZBTB33 Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing

Ellen M. Beauchamp, Matthew Leventhal, Elsa Bernard, Emma R. Hoppe, Gabriele Todisco, Maria Creignou, Anna Gallì, Cecilia A. Castellano, Marie McConkey, Akansha Tarun, Waihay Wong, Monica Schenone, Caroline Stanclift, Benjamin Tanenbaum, Edyta Malolepsza, Björn Nilsson, Alexander G. Bick, Joshua S. Weinstock, Mendy Miller, Abhishek Niroula, Andrew Dunford, Amaro Taylor-Weiner, Timothy Wood, Alex Barbera, Shankara Anand, Bruce M. Psaty, Pinkal Desai, Michael H. Cho, Andrew D. Johnson, Ruth Loos, for the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Daniel G. MacArthur, Monkol Lek, for the Exome Aggregation Consortium, Donna S. Neuberg, Kasper Lage, Steven A. Carr, Eva Hellstrom-Lindberg, Luca Malcovati, Elli Papaemmanuil, Chip Stewart, Gad Getz, Robert K. Bradley, Siddhartha Jaiswal, Benjamin L. Ebert
Journal: Blood Cancer Discovery
Blood Cancer Discov (2021) 2 (5): 500–517.
https://doi.org/10.1158/2643-3230.BCD-20-0224
Published: 01 September 2021
View article titled, <em>ZBTB33</em> Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing
Open the PDF for <em>ZBTB33</em> Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing in another window
Includes: Supplementary data
Journal Articles

Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies

Aline Renneville, Jessica A. Gasser, Daniel E. Grinshpun, Pierre M. Jean Beltran, Namrata D. Udeshi, Mary E. Matyskiela, Thomas Clayton, Marie McConkey, Kaushik Viswanathan, Alexander Tepper, Andrew A. Guirguis, Rob S. Sellar, Sophie Cotteret, Christophe Marzac, Véronique Saada, Stéphane De Botton, Jean-Jacques Kiladjian, Jean-Michel Cayuela, Mark Rolfe, Philip P. Chamberlain, Steven A. Carr, Benjamin L. Ebert
Journal: Blood Cancer Discovery
Blood Cancer Discov (2021) 2 (3): 250–265.
https://doi.org/10.1158/2643-3230.BCD-20-0105
Published: 01 May 2021
View article titled, Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
Open the PDF for Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies in another window
Includes: Supplementary data